{"id":"W2075364976","doi":"10.1371/journal.pone.0040522","title":"Dopamine Receptor-Interacting Protein 78 Acts as a Molecular Chaperone for CCR5 Chemokine Receptor Signaling Complex Organization","year":2012,"lang":"en","type":"article","venue":"PLoS ONE","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University","funders":"Canadian Institutes of Health Research; Dalhousie University; Terry Fox Foundation; Natural Sciences and Engineering Research Council of Canada; Dalhousie Medical Research Foundation; Beatrice Hunter Cancer Research Institute; Cancer Research Institute","keywords":"Chemokine receptor; Cell biology; C-C chemokine receptor type 6; G protein-coupled receptor; Receptor; CCR3; Biology; CCR1; Chemokine receptor CCR5; CCL21; Immune receptor; Signal transduction; Chaperone (clinical); CC chemokine receptors; Chemokine; 5-HT5A receptor; CCR2; CCL7; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001054735,0.0002191249,0.0002662425,0.0001567442,0.0002744042,0.0002149537,0.0002457047,0.0001850981,0.001736539],"category_scores_gemma":[0.0001067743,0.00007619245,0.0002453723,0.0000999549,0.0001438631,0.000153937,0.0001953337,0.0003469541,0.0006801031],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004061725,"about_ca_system_score_gemma":0.0002037032,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000493359,"about_ca_topic_score_gemma":0.0007661282,"domain_scores_codex":[0.9998822,0.00001818078,0.000007523499,0.00002124661,0.00003600893,0.00003487537],"domain_scores_gemma":[0.9999435,0.000003446869,0.00001608311,0.00000768674,0.000008828655,0.00002044177],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001054975,0.00002110059,0.0003996347,0.00004285384,0.000007934394,0.0001238143,0.00001388946,0.00004680732,0.9948683,0.0002285125,0.0002156474,0.003925995],"study_design_scores_gemma":[0.00003157388,0.0001720314,0.01479135,0.00001531918,0.00002084424,0.0009720673,0.00004369325,0.001148172,0.9654875,0.0001467572,0.01715916,0.00001155523],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9793177,0.007937186,0.00597695,0.0004477152,0.0001222701,0.00004831698,0.0005669025,0.0001513465,0.005431788],"genre_scores_gemma":[0.9885913,0.002077364,0.004465026,0.00008804887,0.00002168294,0.00002886506,0.0006217227,0.00002571119,0.004080253],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001736539,"threshold_uncertainty_score":0.005809367,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0485210742050792,"score_gpt":0.2644501282225295,"score_spread":0.2159290540174503,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}