{"id":"W2075376229","doi":"10.1182/blood-2014-09-600858","title":"Microtubule sliding drives proplatelet elongation and is dependent on cytoplasmic dynein","year":2014,"lang":"en","type":"article","venue":"Blood","topic":"Platelet Disorders and Treatments","field":"Medicine","cited_by":112,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Division of Materials Research; National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; Materials Research Science and Engineering Center, Harvard University; Deutsche Forschungsgemeinschaft; National Science Foundation; National Institutes of Health; Department of Physics, Harvard University; Harvard University","keywords":"Microtubule; Cell biology; Cytoplasm; Differential interference contrast microscopy; Tubulin; Dynein; Platelet; Cytoskeleton; Biophysics; Biology; Fluorescence microscope; Elongation; Chemistry; Biochemistry; Fluorescence; Cell; Microscopy; Immunology; Materials science; Medicine; Pathology; Physics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005396439,0.000145711,0.00008581101,0.0001094092,0.0001265194,0.0001918015,0.00009822465,0.0001015631,0.0006316314],"category_scores_gemma":[0.0001190916,0.0001110858,0.00007486164,0.00006921602,0.0001507925,0.0001105385,0.000148957,0.0002639299,0.0001931796],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001689682,"about_ca_system_score_gemma":0.0001130438,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004114519,"about_ca_topic_score_gemma":0.0007523678,"domain_scores_codex":[0.9999456,0.000006106469,0.00000428061,0.00001182699,0.00002119522,0.00001089896],"domain_scores_gemma":[0.9999205,0.00001773607,0.00003017668,0.000008557483,0.00000863614,0.00001445299],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006736069,0.000005171917,0.0002356376,0.00001418938,0.000001846499,0.00005228056,0.00000855671,0.00003361987,0.997866,0.00009814953,0.00003008609,0.001587117],"study_design_scores_gemma":[0.00001805438,0.0001191431,0.0213281,0.000008760359,0.000007191925,0.0003278373,0.0000176602,0.001462806,0.9746981,0.00007610084,0.001931853,0.000004306376],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9952619,0.001144848,0.001832237,0.00008154727,0.000008325304,0.000007331349,0.00008119163,0.00006367221,0.001519012],"genre_scores_gemma":[0.9977848,0.0006987049,0.0006478102,0.00001432967,0.000005249345,0.000007310729,0.00008071688,0.000007706911,0.0007533628],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006316314,"threshold_uncertainty_score":0.002112985,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007649152559041442,"score_gpt":0.2273505563778149,"score_spread":0.2197014038187735,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}