{"id":"W2075376229","doi":"10.1182/blood-2014-09-600858","title":"Microtubule sliding drives proplatelet elongation and is dependent on cytoplasmic dynein","year":2014,"lang":"en","type":"article","venue":"Blood","topic":"Platelet Disorders and Treatments","field":"Medicine","cited_by":112,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Division of Materials Research; National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; Materials Research Science and Engineering Center, Harvard University; Deutsche Forschungsgemeinschaft; National Science Foundation; National Institutes of Health; Department of Physics, Harvard University; Harvard University","keywords":"Microtubule; Cell biology; Cytoplasm; Differential interference contrast microscopy; Tubulin; Dynein; Platelet; Cytoskeleton; Biophysics; Biology; Fluorescence microscope; Elongation; Chemistry; Biochemistry; Fluorescence; Cell; Microscopy; Immunology; Materials science; Medicine; Pathology; Physics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006335812,0.0001164102,0.0001831583,0.00006214644,0.00008091881,0.00002166217,0.00002701251,0.00006298234,0.00003640615],"category_scores_gemma":[0.00002432348,0.00009304169,0.00003132993,0.00004570318,0.00001517416,0.00004269273,0.0000156832,0.00008094362,0.00008477834],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001287727,"about_ca_system_score_gemma":0.0000142834,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001496951,"about_ca_topic_score_gemma":0.0000087708,"domain_scores_codex":[0.9993671,0.00001739354,0.0001114565,0.0002216207,0.000123479,0.0001589149],"domain_scores_gemma":[0.9997039,0.00002766776,0.00004091082,0.0001345977,0.00001913688,0.00007379729],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007350153,0.006809604,0.5226904,0.0006136896,0.001403274,0.001803916,0.0049045,0.000008264223,0.3723676,0.001974687,0.003003971,0.08368512],"study_design_scores_gemma":[0.01954149,0.002152569,0.07266648,0.0003718575,0.0005534356,0.001134685,0.0001667067,0.0005447989,0.8966584,0.001018057,0.004773626,0.00041786],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9968229,0.0001574081,0.0000372844,0.0004505772,0.00003753488,0.0002592964,0.000005796745,0.00004014737,0.002189036],"genre_scores_gemma":[0.9985312,0.00008899596,0.0003897806,0.0004511337,0.0000399944,0.0000146669,0.00002529839,0.00001521132,0.0004437187],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5242908,"threshold_uncertainty_score":0.379413,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007649152559041442,"score_gpt":0.2273505563778149,"score_spread":0.2197014038187735,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}