{"id":"W2075456955","doi":"10.1016/j.mcna.2012.01.018","title":"Genomics: Is It Ready for Primetime?","year":2012,"lang":"en","type":"review","venue":"Medical Clinics of North America","topic":"Genetic Associations and Epidemiology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Ottawa; McGill University","funders":"","keywords":"Missing heritability problem; Medicine; Single-nucleotide polymorphism; Heritability; Genomics; Interrogation; Coronary artery disease; Genetic association; Computational biology; Genome-wide association study; Bioinformatics; Genetics; Biology; Gene; Internal medicine; Genome; Genotype","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0009647067,0.0003388978,0.001751398,0.00005882698,0.0000561308,0.000004009625,0.0006202469,0.0008500298,0.0002107522],"category_scores_gemma":[0.002418567,0.0002812867,0.0008020695,0.0001192059,0.0002711518,0.000001219565,0.0002424929,0.0003106426,0.0001019237],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002530769,"about_ca_system_score_gemma":0.0009053684,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000183552,"about_ca_topic_score_gemma":0.00001926122,"domain_scores_codex":[0.9971162,0.0002352231,0.001411527,0.0005166667,0.0002347212,0.0004856537],"domain_scores_gemma":[0.9971184,0.0005436339,0.001181382,0.0006663019,0.0001612015,0.000329069],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000008597225,0.0001051787,0.0006546412,0.001012426,0.0003384412,2.816422e-7,0.00001213298,5.23497e-7,1.564861e-7,0.000002336898,0.02875199,0.9691133],"study_design_scores_gemma":[0.0001838473,0.0003467459,0.00009334666,0.000171752,0.000591535,0.000004252041,0.000006604992,0.00001340989,6.196681e-7,0.00001068604,0.9983099,0.0002673642],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001268838,0.9941388,0.003408208,0.0002591702,0.0004297813,0.000601625,0.0006248109,0.000006427609,0.0004043311],"genre_scores_gemma":[0.0000299477,0.9867706,0.006413639,0.00172202,0.001009199,0.0001349914,0.003016304,0.0000573789,0.000845873],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9695578,"threshold_uncertainty_score":0.9999639,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09492310673075352,"score_gpt":0.4119401867012468,"score_spread":0.3170170799704933,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}