{"id":"W2075458520","doi":"10.1016/j.pneurobio.2013.07.006","title":"Levels and actions of progesterone and its metabolites in the nervous system during physiological and pathological conditions","year":2013,"lang":"en","type":"review","venue":"Progress in Neurobiology","topic":"Estrogen and related hormone effects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":123,"is_retracted":false,"has_abstract":false,"ca_institutions":"Baycrest Hospital","funders":"Fondazione Cariplo","keywords":"Neuroactive steroid; Allopregnanolone; Neuroprotection; Central nervous system; Hormone; Neuroscience; Aromatase; Endocrinology; Dehydroepiandrosterone; Biology; Estrogen; Internal medicine; Nervous system; Medicine; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001804998,0.000273673,0.000779255,0.00009195272,0.00006136876,0.00001738933,0.0001496391,0.000564513,0.000001477074],"category_scores_gemma":[0.00005170859,0.0001563892,0.00006980511,0.0001104003,0.000410483,0.000005101088,0.0002329442,0.0003958842,0.000001226035],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00000541855,"about_ca_system_score_gemma":0.00002064347,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":9.36284e-7,"about_ca_topic_score_gemma":7.541189e-7,"domain_scores_codex":[0.998036,0.0008147119,0.000379704,0.0004785671,0.00003644932,0.0002546245],"domain_scores_gemma":[0.9994786,0.00008547965,0.0001938958,0.0001768978,0.00002188403,0.00004327742],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.0002519698,0.002304806,0.01826962,0.08253397,0.001408053,0.001004644,0.0007658727,0.000009332594,0.2438575,0.01110761,0.0001061707,0.6383805],"study_design_scores_gemma":[0.01336272,0.01735198,0.7257885,0.0294617,0.005199724,0.05589675,0.001494799,0.0002005217,0.02049465,0.000438614,0.1226049,0.007705084],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.4742212,0.5251056,1.239126e-7,0.00001253789,0.00002811631,0.0005893326,0.00003007989,0.000005379819,0.000007626321],"genre_scores_gemma":[0.4320079,0.5675039,0.0000226492,0.000007756731,0.00002846397,0.0003688929,0.00004450212,0.00001040805,0.000005495283],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.7075189,"threshold_uncertainty_score":0.6377366,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0544815082026699,"score_gpt":0.3353465696346431,"score_spread":0.2808650614319732,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}