{"id":"W2075469643","doi":"10.1128/iai.06066-11","title":"Campylobacter jejuni Disrupts Protective Toll-Like Receptor 9 Signaling in Colonic Epithelial Cells and Increases the Severity of Dextran Sulfate Sodium-Induced Colitis in Mice","year":2012,"lang":"en","type":"article","venue":"Infection and Immunity","topic":"Helicobacter pylori-related gastroenterology studies","field":"Medicine","cited_by":61,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Campylobacter jejuni; Biology; Colitis; Immunology; Microbiology; Interleukin 22; TLR9; Immune system; Inflammatory bowel disease; Inflammation; Cytokine; Interleukin; Internal medicine; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003244745,0.0008013807,0.0005268219,0.0007727621,0.0003302673,0.0004314957,0.0005090658,0.001302424,0.002219656],"category_scores_gemma":[0.0002867494,0.0005754842,0.0006137523,0.0002951782,0.0005992448,0.0003687132,0.0003887917,0.002190481,0.0006967092],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009572944,"about_ca_system_score_gemma":0.0006312588,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002247688,"about_ca_topic_score_gemma":0.00318252,"domain_scores_codex":[0.9992532,0.000121684,0.00008898294,0.0001473854,0.0001472328,0.0002414949],"domain_scores_gemma":[0.9994395,0.00005471548,0.0001347636,0.00005789929,0.00003326266,0.0002798117],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008166949,0.0004892087,0.0001898205,0.00006327094,0.00001242106,0.0001044135,0.00004439999,0.00009682804,0.9971192,0.00008522168,0.0001163721,0.0008622542],"study_design_scores_gemma":[0.0003115226,0.006098522,0.01669464,0.00007029377,0.00006332925,0.0006420277,0.0002179025,0.002929755,0.9690251,0.0001828202,0.003727536,0.00003661171],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9937974,0.00117309,0.001284692,0.000573741,0.0001432467,0.00008934391,0.0009509785,0.0002366366,0.001750809],"genre_scores_gemma":[0.991506,0.000718415,0.0021116,0.0003518883,0.00002298044,0.0001392688,0.0008432466,0.00006538253,0.00424127],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002247688,"threshold_uncertainty_score":0.007425487,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01721318390417257,"score_gpt":0.2584135935363745,"score_spread":0.2412004096322019,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}