{"id":"W2075489745","doi":"10.1016/j.chom.2007.11.005","title":"Ub Surprised: Viral Ovarian Tumor Domain Proteases Remove Ubiquitin and ISG15 Conjugates","year":2007,"lang":"en","type":"review","venue":"Cell Host & Microbe","topic":"interferon and immune responses","field":"Immunology and Microbiology","cited_by":17,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University; Jewish General Hospital","funders":"","keywords":"ISG15; Biology; Proteases; Ubiquitin; Virology; Cell biology; Protease; Biochemistry; Enzyme; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003881393,0.001191689,0.00122704,0.0006134999,0.0002094343,0.0008582735,0.0007560307,0.001217385,0.001350775],"category_scores_gemma":[0.0002088893,0.0002831111,0.000285549,0.0007271071,0.0004526436,0.0009596518,0.000483084,0.00124769,0.002285458],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007016296,"about_ca_system_score_gemma":0.0004755974,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003162475,"about_ca_topic_score_gemma":0.0006190402,"domain_scores_codex":[0.9998853,0.00001082993,0.00001060792,0.00002033774,0.000054456,0.00001841702],"domain_scores_gemma":[0.9999264,0.00001731286,0.00001831431,0.000005494042,0.000020618,0.00001174062],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002708873,0.00008345552,0.0001934634,0.002568135,0.00005911949,0.0005202044,0.0000255895,0.0005101974,0.04032702,0.003612034,0.02870071,0.9231292],"study_design_scores_gemma":[0.0000552101,0.0001547023,0.0008457096,0.0002488618,0.00006226731,0.002084622,0.00003319616,0.0003409006,0.04248659,0.001748586,0.9519177,0.00002158727],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00227876,0.9877259,0.003053713,0.0007419552,0.00133812,0.00002486605,0.00007604116,0.0000919641,0.004668746],"genre_scores_gemma":[0.009510102,0.9740672,0.002344097,0.0007972101,0.0005699834,0.00003839377,0.0002449117,0.00001452022,0.01241348],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001350775,"threshold_uncertainty_score":0.005090773,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02146289942386655,"score_gpt":0.2889305229507708,"score_spread":0.2674676235269043,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}