{"id":"W2075524647","doi":"10.1084/jem.20052444","title":"Lineage specification and plasticity in CD19− early B cell precursors","year":2006,"lang":"en","type":"article","venue":"The Journal of Experimental Medicine","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":194,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institutes of Health; University of Toronto; National Institute of Allergy and Infectious Diseases; Oklahoma Medical Research Foundation","keywords":"Lineage (genetic); Biology; CD19; B cell; Myeloid; Lineage markers; Progenitor cell; Flow cytometry; Cell biology; Progenitor; Lymphopoiesis; Recombination-activating gene; Cellular differentiation; Molecular biology; Stem cell; Genetics; Immunology; Gene; Antibody; Recombination","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001066906,0.0001575889,0.0001252374,0.000344646,0.0002366641,0.000474824,0.0001461423,0.0001923676,0.001192041],"category_scores_gemma":[0.0002000148,0.0001365966,0.0001307986,0.00009298938,0.0001167027,0.0002020279,0.0002624537,0.0003998852,0.0005935834],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001366602,"about_ca_system_score_gemma":0.0001083303,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004075504,"about_ca_topic_score_gemma":0.0006350765,"domain_scores_codex":[0.9999077,0.00001200564,0.00001079696,0.00002141335,0.00002312599,0.00002489128],"domain_scores_gemma":[0.9998609,0.00003708659,0.00002268571,0.00001584644,0.00001907092,0.00004445236],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007397712,0.000009435636,0.001447829,0.00001589524,0.000001315814,0.00007864009,0.00004013981,0.00003314525,0.9945128,0.000166991,0.00001877898,0.003601158],"study_design_scores_gemma":[0.00002235094,0.0002762513,0.03436821,0.00001243059,0.00001612744,0.001404298,0.0001040446,0.0006732637,0.9581999,0.0003196492,0.004594214,0.000009324832],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9917863,0.0008151599,0.005354595,0.00003071021,0.000006582704,0.0000343642,0.0002476454,0.00008096837,0.001643663],"genre_scores_gemma":[0.9875926,0.0007990384,0.008234726,0.00004613777,0.000009343745,0.00005553799,0.0007221671,0.00003749115,0.002502892],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001192041,"threshold_uncertainty_score":0.00398773,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01191130432501811,"score_gpt":0.2369694804576406,"score_spread":0.2250581761326225,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}