{"id":"W2075704285","doi":"10.1002/humu.21091","title":"Common epigenetic changes of D4Z4 in contraction-dependent and contraction-independent FSHD","year":2009,"lang":"en","type":"article","venue":"Human Mutation","topic":"Muscle Physiology and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":209,"is_retracted":false,"has_abstract":true,"ca_institutions":"London Health Sciences Centre","funders":"","keywords":"Facioscapulohumeral muscular dystrophy; Subtelomere; Epigenetics; DNA methylation; Biology; Genetics; Chromosome; Haplotype; Muscular dystrophy; Gene; Genotype","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001489045,0.0002577502,0.0002176042,0.0006227202,0.0001967962,0.0001435752,0.000240053,0.0002925631,0.001440223],"category_scores_gemma":[0.0003878272,0.0002042434,0.0003358478,0.000229503,0.0003471181,0.0001010717,0.0004004978,0.0002091527,0.0001693686],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002494474,"about_ca_system_score_gemma":0.0001533129,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008826572,"about_ca_topic_score_gemma":0.00140241,"domain_scores_codex":[0.9998688,0.00001960905,0.00001526291,0.00004317237,0.00002963644,0.00002346144],"domain_scores_gemma":[0.9998457,0.0000329303,0.000056384,0.0000225896,0.0000180828,0.00002416483],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006999722,0.00002852303,0.07041785,0.00007345624,0.00008871684,0.002665356,0.0001657041,0.0001765557,0.9140533,0.000318419,0.0001306702,0.01118151],"study_design_scores_gemma":[0.000151815,0.000494135,0.6588499,0.0000264432,0.0002185318,0.01643525,0.0001731311,0.0008910433,0.3174451,0.0006237475,0.004654367,0.00003652309],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9960033,0.0009425212,0.001795899,0.00004873446,0.000009866056,0.00002235311,0.0002699615,0.0000416943,0.0008656566],"genre_scores_gemma":[0.9977196,0.0003049997,0.0007056292,0.00004742949,0.000005987761,0.00001782015,0.0003311505,0.000009276943,0.0008581564],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001440223,"threshold_uncertainty_score":0.004818022,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01085930773313752,"score_gpt":0.2777779909053874,"score_spread":0.2669186831722498,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}