{"id":"W2075755442","doi":"10.1161/01.cir.0000112583.50762.de","title":"Endoproteolytic Activation of α <sub>v</sub> Integrin by Proprotein Convertase PC5 Is Required for Vascular Smooth Muscle Cell Adhesion to Vitronectin and Integrin-Dependent Signaling","year":2004,"lang":"en","type":"article","venue":"Circulation","topic":"Cell Adhesion Molecules Research","field":"Medicine","cited_by":34,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"Canadian Institutes of Health Research; Bundesministerium für Bildung und Forschung","keywords":"Integrin; Vitronectin; Vascular smooth muscle; Cell biology; Cell adhesion; Focal adhesion; Signal transduction; Proprotein convertase; Cell adhesion molecule; Biology; Phosphorylation; Biochemistry; Cell; Endocrinology; LDL receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001287058,0.0003392421,0.0001987299,0.0001473519,0.0001460656,0.0004000251,0.000134157,0.0001970925,0.001057339],"category_scores_gemma":[0.0001677616,0.00009131261,0.0002946586,0.0001202233,0.0001921093,0.000165466,0.0001109487,0.0004754669,0.0002669654],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004245589,"about_ca_system_score_gemma":0.0002515707,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008279758,"about_ca_topic_score_gemma":0.0007243114,"domain_scores_codex":[0.9998143,0.00002687573,0.00001895399,0.00003581727,0.00004940191,0.00005470791],"domain_scores_gemma":[0.9998474,0.00002474814,0.00005737534,0.00001222573,0.00001950252,0.00003867488],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002065307,0.00002424239,0.0003752717,0.00003074355,0.000005676408,0.00005768007,0.000006963993,0.00002495703,0.9983042,0.00006832708,0.00001999489,0.0008753076],"study_design_scores_gemma":[0.00001514931,0.0002169619,0.01424384,0.00000722617,0.00001978328,0.0003120777,0.00002520935,0.0006270657,0.9834545,0.00003642184,0.001039517,0.000002226359],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9929463,0.002782254,0.003075776,0.00006592745,0.00001996926,0.00002052792,0.0001845342,0.00002365405,0.0008810289],"genre_scores_gemma":[0.9950696,0.0008806075,0.002111988,0.00004014314,0.00001344328,0.00002350162,0.0005775678,0.000007780855,0.001275394],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001057339,"threshold_uncertainty_score":0.003537118,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01978602025820584,"score_gpt":0.2629638798920759,"score_spread":0.24317785963387,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}