{"id":"W2075774801","doi":"10.1007/s004419900165","title":"Etidronate (HEBP) promotes osteoblast differentiation and wound closure in rat calvaria","year":2000,"lang":"en","type":"article","venue":"Cell and Tissue Research","topic":"Bone health and treatments","field":"Medicine","cited_by":39,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Manitoba; Medical Council of Canada; University of Toronto","funders":"","keywords":"Osteoid; Osteopontin; Bone sialoprotein; Osteoblast; Calvaria; Wound healing; Endocrinology; Osteocalcin; Chemistry; Cellular differentiation; Bone resorption; Internal medicine; Cell biology; Biology; Anatomy; Immunology; Alkaline phosphatase; Medicine; In vitro; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002995145,0.00009261045,0.0001744148,0.0001231709,0.000126055,0.00003532983,0.000026652,0.000106337,0.0004683075],"category_scores_gemma":[0.00002018192,0.00007259405,0.00001059659,0.00018434,0.00008838793,0.00005390695,0.00002631972,0.0003043733,0.00009970042],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003902512,"about_ca_system_score_gemma":0.00007287645,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006972201,"about_ca_topic_score_gemma":0.0002528114,"domain_scores_codex":[0.9988713,0.0001176415,0.0001444273,0.0002542512,0.0002525598,0.0003598249],"domain_scores_gemma":[0.9994905,0.00008639147,0.00001293105,0.0001282893,0.00004650349,0.0002353853],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001155327,0.0008801925,0.4943188,0.001427489,0.00004059294,0.0005279144,0.002473691,5.581911e-7,0.01247758,0.0002764855,0.0008827618,0.4855386],"study_design_scores_gemma":[0.008674632,0.002039999,0.9242182,0.0003053151,0.00004242816,0.0001104957,0.0001506745,0.0003685388,0.01977631,0.001675334,0.04241717,0.0002208517],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9894599,0.00273323,8.889288e-7,0.001705808,0.00002265343,0.0006286143,0.000003350456,0.0000123746,0.005433148],"genre_scores_gemma":[0.9820457,0.001270802,0.0000590366,0.00002665033,0.00004425221,0.0000335252,0.00003179421,0.00001257027,0.01647566],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4853177,"threshold_uncertainty_score":0.5127639,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03659589988927491,"score_gpt":0.3545051676357411,"score_spread":0.3179092677464662,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}