{"id":"W2075841564","doi":"10.1038/leu.2014.67","title":"Epigenetic regulation of GATA2 and its impact on normal karyotype acute myeloid leukemia","year":2014,"lang":"en","type":"article","venue":"Leukemia","topic":"Acute Myeloid Leukemia Research","field":"Medicine","cited_by":38,"is_retracted":false,"has_abstract":false,"ca_institutions":"Leukemia & Lymphoma Society of Canada; Hôpital Maisonneuve-Rosemont; Université de Montréal; Institute for Research in Immunology and Cancer","funders":"Louisiana State University","keywords":"GATA2; Myeloid leukemia; Biology; Cancer research; Epigenetics; Leukemia; Genetics; Myeloid; Gene; Transcription factor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005578021,0.0003485228,0.0006161057,0.0003394383,0.0001093535,0.00002669926,0.0002285983,0.0003047055,0.0002783701],"category_scores_gemma":[0.0003006843,0.0002779207,0.0001646563,0.000437224,0.0001571108,0.0001678122,0.0001439181,0.00057829,0.0002225658],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001954994,"about_ca_system_score_gemma":0.001078502,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002232616,"about_ca_topic_score_gemma":0.00001224279,"domain_scores_codex":[0.997586,0.0001385668,0.0004913709,0.0005137189,0.0006652593,0.0006051038],"domain_scores_gemma":[0.998191,0.0002718532,0.0001907941,0.000703426,0.0002339249,0.0004089836],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.007176326,0.0001696912,0.04087589,0.0009492146,0.001070723,0.0001530983,0.001016154,0.003301543,0.824496,0.004014249,0.01902648,0.09775063],"study_design_scores_gemma":[0.005033417,0.002515143,0.7601932,0.0002683329,0.0002710083,0.0002525613,0.00003807683,0.04590926,0.1826457,0.0004302509,0.002032191,0.0004108448],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9889187,0.0002667569,0.0002756197,0.0003424881,0.0001054091,0.0005426731,0.00002837868,0.00008433391,0.009435644],"genre_scores_gemma":[0.9953387,0.0002574791,0.0006849639,0.0003870663,0.0003700314,0.0000200625,0.000115792,0.00007070266,0.002755156],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7193173,"threshold_uncertainty_score":0.9999673,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01300739037023071,"score_gpt":0.2941993326760852,"score_spread":0.2811919423058545,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}