{"id":"W2075853386","doi":"10.1593/tlo.13136","title":"Anti-VEGFA Therapy Reduces Tumor Growth and Extends Survival in a Murine Model of Ovarian Granulosa Cell Tumor","year":2013,"lang":"en","type":"article","venue":"Translational Oncology","topic":"Ovarian cancer diagnosis and treatment","field":"Medicine","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"Cegep de Saint Hyacinthe; McGill University; Université de Montréal","funders":"Canadian Institutes of Health Research; Genentech","keywords":"Vascular endothelial growth factor A; Angiogenesis; Cancer research; PTEN; Cell growth; MAPK/ERK pathway; Kinase insert domain receptor; Apoptosis; Vascular endothelial growth factor; Adjuvant therapy; Medicine; Internal medicine; Biology; Endocrinology; Kinase; Cancer; PI3K/AKT/mTOR pathway; Cell biology; VEGF receptors","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001385754,0.0001540522,0.0004876894,0.0001513913,0.00002871516,0.00000619685,0.00005298682,0.00006499984,0.0002680609],"category_scores_gemma":[0.000007121557,0.0001251323,0.00007188622,0.000144083,0.000112567,0.00009295723,0.000007666747,0.000121616,0.000005577693],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004115337,"about_ca_system_score_gemma":0.0003237858,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004115753,"about_ca_topic_score_gemma":0.00006801432,"domain_scores_codex":[0.9989084,0.00006130709,0.0003679987,0.0002782226,0.00018568,0.0001983987],"domain_scores_gemma":[0.9994482,0.0001619794,0.00009757778,0.000111217,0.0000816372,0.00009942328],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.002940779,0.01217508,0.6960758,0.0005441535,0.000560567,0.0004051864,0.004258264,0.001499092,0.1989858,0.02941324,0.0004757749,0.05266633],"study_design_scores_gemma":[0.01295753,0.001171242,0.9607937,0.00005757366,0.00008208449,0.00004534434,0.0000659146,0.005822108,0.01341382,0.005089903,0.0003189826,0.0001817332],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9833866,0.0007839426,0.0001169788,0.008612621,0.00007814683,0.0005422155,0.00004101713,0.00001563862,0.006422814],"genre_scores_gemma":[0.993951,0.0003131823,0.00507119,0.0003661259,0.00007587351,0.0001197599,0.00003676392,0.00001778781,0.00004829628],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.264718,"threshold_uncertainty_score":0.5102749,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03016251600989728,"score_gpt":0.2901945666499952,"score_spread":0.2600320506400979,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}