{"id":"W2075855938","doi":"10.1016/j.bbagrm.2011.12.004","title":"Discovering genome regulation with 3C and 3C-related technologies","year":2011,"lang":"en","type":"review","venue":"Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":39,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University","funders":"Canadian Institutes of Health Research","keywords":"Chromatin; Biology; Chromosome conformation capture; Genome; Computational biology; DNA; Interphase; Chromosome; Genetics; Replication timing; Genomics; Genomic organization; DNA replication; Transcription factor; Gene; Enhancer","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002687544,0.001116214,0.001391804,0.000264559,0.0002380029,0.0001280852,0.0007959335,0.001193226,0.00001044735],"category_scores_gemma":[0.00001736588,0.0009349278,0.0004597779,0.0003369583,0.0003440081,0.00002239853,0.0007855629,0.0004088589,0.00001687301],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009987019,"about_ca_system_score_gemma":0.000308637,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00000699237,"about_ca_topic_score_gemma":0.000006863371,"domain_scores_codex":[0.9966102,0.0001530175,0.0008193615,0.001498207,0.0002770558,0.000642193],"domain_scores_gemma":[0.997166,0.00001863626,0.0009509276,0.001615427,0.00009006917,0.0001589534],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004869837,0.0001232637,4.76554e-8,0.001574911,0.0008634579,0.00000750794,0.0000847574,0.000008931189,0.9522491,0.00392066,0.00003254598,0.04108613],"study_design_scores_gemma":[0.001079926,0.001395576,0.0001258463,0.002638195,0.002098661,0.0004621352,0.0001653228,0.0001325351,0.9457895,0.004155617,0.0385239,0.003432753],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.3674335,0.6288274,0.00123663,0.00004543264,0.0002539124,0.001437895,0.0003153457,0.0002401671,0.0002097311],"genre_scores_gemma":[0.1259303,0.8667003,0.004645258,0.00002625439,0.0001299804,0.000161145,0.0016879,0.0003018406,0.0004169893],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.2415032,"threshold_uncertainty_score":0.9993101,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01249443137563665,"score_gpt":0.2287936104074428,"score_spread":0.2162991790318061,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}