{"id":"W2075855948","doi":"10.1002/pmic.201200458","title":"Proteolytic factors in exosomes","year":2013,"lang":"en","type":"review","venue":"PROTEOMICS","topic":"Extracellular vesicles in disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":94,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ontario Institute for Cancer Research","funders":"Canadian Institutes of Health Research","keywords":"Microvesicles; Proteases; Cell biology; Matrix metalloproteinase; Ectodomain; Biology; Disintegrin; Endosome; Exosome; Extracellular matrix; Metalloproteinase; Cell; Proteolytic enzymes; Biochemistry; microRNA; Intracellular; Receptor; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003817707,0.0008005861,0.001068789,0.001587066,0.0003439709,0.001300855,0.0004413221,0.001405453,0.001694135],"category_scores_gemma":[0.000446182,0.0002481116,0.0004669188,0.00123823,0.0005902686,0.001459065,0.0009578554,0.001413955,0.001538002],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005060476,"about_ca_system_score_gemma":0.0007219844,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004767235,"about_ca_topic_score_gemma":0.0004016849,"domain_scores_codex":[0.9997477,0.00004065005,0.00004239815,0.00004824896,0.00009397116,0.00002711712],"domain_scores_gemma":[0.9998649,0.00004752939,0.00002868266,0.000006629303,0.00003538004,0.00001675905],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001326004,0.00006269263,0.0005109799,0.01778458,0.0001236153,0.001759621,0.0002377456,0.0003858027,0.03519198,0.01550622,0.02311454,0.9051896],"study_design_scores_gemma":[0.00001405362,0.00005783395,0.001217865,0.001823493,0.00007924574,0.00692948,0.00009880724,0.00008567992,0.01014278,0.003882551,0.9756396,0.00002867688],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0005922723,0.9964213,0.0006705895,0.000277995,0.0003365225,0.0000104497,0.00004660642,0.0000166988,0.001627523],"genre_scores_gemma":[0.004299815,0.9921416,0.0009336537,0.0002479201,0.0002859533,0.00001913007,0.0001039221,0.000004434079,0.00196354],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001694135,"threshold_uncertainty_score":0.005667448,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03953853445578017,"score_gpt":0.3162043114855291,"score_spread":0.2766657770297489,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}