{"id":"W2075881224","doi":"10.1007/s00280-007-0544-2","title":"Identification, characterization and potent antitumor activity of ECO-4601, a novel peripheral benzodiazepine receptor ligand","year":2007,"lang":"en","type":"article","venue":"Cancer Chemotherapy and Pharmacology","topic":"Synthesis and pharmacology of benzodiazepine derivatives","field":"Chemistry","cited_by":53,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Montréal","funders":"","keywords":"Pharmacology; In vivo; Glioma; Receptor; Cell culture; Chemistry; Biology; Cancer research; Biochemistry; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001847266,0.0002999567,0.0002979687,0.0002138541,0.0001261975,0.0002720602,0.0002388016,0.0001888823,0.0006304949],"category_scores_gemma":[0.0001824024,0.000137395,0.0001424846,0.0001681389,0.0001730435,0.0001886805,0.0001519135,0.0003758984,0.0004740782],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002712438,"about_ca_system_score_gemma":0.0003588824,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008157133,"about_ca_topic_score_gemma":0.001033568,"domain_scores_codex":[0.999913,0.00001802066,0.000006370083,0.00001418227,0.00002705986,0.00002139994],"domain_scores_gemma":[0.9999299,0.000008792741,0.00001866671,0.000008186753,0.00001133721,0.00002306194],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002193914,0.0001105923,0.0004409345,0.00004304059,0.000006173538,0.0001203067,0.00002722246,0.0004166971,0.9904811,0.0001566931,0.000106193,0.007871731],"study_design_scores_gemma":[0.000181034,0.002602469,0.006634262,0.00001103277,0.00004457723,0.002249618,0.00004262312,0.002264509,0.9741729,0.00009974867,0.01167779,0.00001944358],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9875485,0.003943999,0.005410743,0.0001823577,0.00001495231,0.00008036984,0.0004630859,0.00005057467,0.002305456],"genre_scores_gemma":[0.9866426,0.003631559,0.004421721,0.00009214234,0.00001364128,0.00004754213,0.001827969,0.00001604226,0.003306752],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008157133,"threshold_uncertainty_score":0.00210923,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01661777123968933,"score_gpt":0.3031539496841207,"score_spread":0.2865361784444314,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}