{"id":"W2075940599","doi":"10.3390/pathogens3030510","title":"Perturbation of the Human Microbiome as a Contributor to Inflammatory Bowel Disease","year":2014,"lang":"en","type":"review","venue":"Pathogens","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":36,"is_retracted":false,"has_abstract":true,"ca_institutions":"Foothills Medical Centre; University of Alberta; University of Calgary; Health Sciences Centre; Alberta Health Services","funders":"","keywords":"Microbiome; Inflammatory bowel disease; Ulcerative colitis; Disease; Immune system; Immunology; Human microbiome; Human Microbiome Project; Etiology; Crohn's disease; Metagenomics; Pathogenesis; Genome; Immune dysregulation; Medicine; Bioinformatics; Biology; Genetics; Gene; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000295215,0.0004142514,0.0005706528,0.00009163942,0.0001364124,0.00002554033,0.0006149836,0.0003051769,0.00003860048],"category_scores_gemma":[0.0004432819,0.0003075339,0.0008413561,0.0001028524,0.0001070294,0.000002311641,0.0003453026,0.0001339711,0.0001231568],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006043574,"about_ca_system_score_gemma":0.0005264995,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000001612368,"about_ca_topic_score_gemma":0.000006482108,"domain_scores_codex":[0.9979931,0.0003665149,0.0006024559,0.0005196129,0.0002024884,0.0003158754],"domain_scores_gemma":[0.9978688,0.0000189849,0.0004444556,0.001199011,0.0001755997,0.0002931861],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001060411,0.001743553,0.008511311,0.2040877,0.004525759,0.001086759,0.0008451557,0.0001277491,0.4015231,0.01379007,0.06169932,0.3009991],"study_design_scores_gemma":[0.000208378,0.00003522366,0.002020793,0.001615365,0.0005605606,0.000008381822,0.00000323104,0.000001026188,0.0002391756,0.00003334644,0.9948743,0.0004002085],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.02378439,0.9713104,0.00004404258,0.00003031014,0.0004519697,0.002184093,0.001707164,0.00002694798,0.0004606423],"genre_scores_gemma":[0.01209714,0.9737303,0.00008667313,0.0009468895,0.00186901,0.0009510527,0.0030886,0.0003379882,0.006892338],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.933175,"threshold_uncertainty_score":0.9999377,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01009512148896428,"score_gpt":0.2753836046788358,"score_spread":0.2652884831898715,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}