{"id":"W2075944172","doi":"10.1182/blood-2012-05-428672","title":"Regulating type 1 IFN effects in CD8 T cells during viral infections: changing STAT4 and STAT1 expression for function","year":2012,"lang":"en","type":"article","venue":"Blood","topic":"Cytokine Signaling Pathways and Interactions","field":"Medicine","cited_by":90,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research; National Center for Research Resources; School of Medicine, Indiana University","keywords":"CD8; Biology; Expression (computer science); Function (biology); Virology; Immunology; Cancer research; Cell biology; Immune system; Computer science","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001482257,0.00009037623,0.0001318305,0.0001949462,0.0001265314,0.0000149227,0.00001190277,0.00004914563,0.00001795166],"category_scores_gemma":[0.0001100717,0.00008229845,0.00003504936,0.0001384407,0.000009531514,0.0001908251,0.00002391162,0.0001142616,0.000004346365],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004011151,"about_ca_system_score_gemma":0.00001897669,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001856201,"about_ca_topic_score_gemma":0.000003871684,"domain_scores_codex":[0.9993821,0.00001969841,0.000147009,0.0001303315,0.00007254212,0.0002482895],"domain_scores_gemma":[0.9996343,0.0001095782,0.00005563287,0.00009264172,0.00003791457,0.00006998544],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001039091,0.0002859753,0.01666635,0.0002287886,0.00001969346,0.000001430958,0.0007391792,0.00002257468,0.9810195,0.00004206789,0.00002974647,0.0008408096],"study_design_scores_gemma":[0.003086194,0.0005245107,0.02774488,0.0005865803,0.0001177045,0.00003454779,0.0002429467,0.0002835524,0.9662659,0.0000513681,0.0009470878,0.0001147954],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9973298,0.0003651601,0.001226663,0.00001647096,0.0004447307,0.0003849123,0.000003596472,0.00005401814,0.0001746638],"genre_scores_gemma":[0.998226,0.00001305735,0.001008381,0.00003183588,0.0004266673,0.00005324668,0.00001545663,0.0000203628,0.0002049478],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01475365,"threshold_uncertainty_score":0.3356034,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01307561659909157,"score_gpt":0.2618015995747104,"score_spread":0.2487259829756189,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}