{"id":"W2075957244","doi":"10.1016/j.pupt.2012.08.006","title":"Models to study airway smooth muscle contraction in vivo, ex vivo and in vitro: Implications in understanding asthma","year":2012,"lang":"en","type":"review","venue":"Pulmonary Pharmacology & Therapeutics","topic":"Inhalation and Respiratory Drug Delivery","field":"Medicine","cited_by":47,"is_retracted":false,"has_abstract":false,"ca_institutions":"Dalhousie University; McGill University; Christie (Canada); University of Manitoba; University of Calgary","funders":"Canadian Institutes of Health Research","keywords":"Ex vivo; In vivo; Contraction (grammar); Airway; Airway hyperresponsiveness; Medicine; Asthma; Pathophysiology; Muscle contraction; Effector; Immunology; Neuroscience; Biology; Pathology; Anatomy; Internal medicine; Anesthesia","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007420403,0.001175027,0.001731251,0.001671193,0.0002493117,0.0008340037,0.001192791,0.001147087,0.001683467],"category_scores_gemma":[0.0003841818,0.000302545,0.0006729669,0.001265529,0.000644776,0.001330829,0.0006745045,0.002525767,0.001430926],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005619611,"about_ca_system_score_gemma":0.0008478077,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009982954,"about_ca_topic_score_gemma":0.002169375,"domain_scores_codex":[0.999765,0.00003410467,0.00002518114,0.00004665167,0.0001054319,0.00002369514],"domain_scores_gemma":[0.9996946,0.0001252435,0.00005736296,0.00001382545,0.00007870478,0.00003038681],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001672237,0.0003664646,0.0004241439,0.01595926,0.0001120437,0.0003298673,0.00007238352,0.0005613203,0.07259761,0.008856444,0.01703957,0.8835136],"study_design_scores_gemma":[0.00004829713,0.000429553,0.002059357,0.00257878,0.0002979923,0.00189093,0.000139313,0.0003516442,0.01629058,0.003439886,0.9724171,0.00005657438],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00061959,0.9953903,0.001559204,0.0003677798,0.0003474399,0.00001715437,0.00005477249,0.0000138396,0.001629865],"genre_scores_gemma":[0.002519903,0.9938025,0.00173577,0.000241107,0.0002154035,0.00003787505,0.00009120008,0.000003477418,0.00135259],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001731251,"threshold_uncertainty_score":0.005631804,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1765216480588406,"score_gpt":0.3900829939883491,"score_spread":0.2135613459295085,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}