{"id":"W2076007110","doi":"10.1158/1538-7445.am2011-267","title":"Abstract 267: E2F1 regulates human TRAIL promoter and mediates Interferon alpha 2a response","year":2011,"lang":"en","type":"article","venue":"Cancer Research","topic":"interferon and immune responses","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"E2F1; E2F; Transcription factor; Transactivation; NFAT; Biology; Chromatin immunoprecipitation; Reporter gene; Transfection; Molecular biology; Cell biology; Promoter; Cancer research; Gene expression; Cell culture; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001579543,0.0006130741,0.0002349801,0.0004967391,0.0002721105,0.000359933,0.0001762833,0.0002895244,0.00667228],"category_scores_gemma":[0.0001827426,0.0001705588,0.0003393451,0.0001861052,0.0001948295,0.0001397317,0.000265227,0.0004614551,0.004298223],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006116159,"about_ca_system_score_gemma":0.0002585975,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00104563,"about_ca_topic_score_gemma":0.0008144392,"domain_scores_codex":[0.9998268,0.0000258469,0.0000114425,0.00003756659,0.0000396945,0.00005867764],"domain_scores_gemma":[0.9998411,0.0000463746,0.00003339129,0.00001432693,0.00002721687,0.00003762599],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002399146,0.00006801243,0.0002429096,0.00004169707,0.000003079783,0.0001069428,0.00002211716,0.00003762166,0.9974317,0.000139277,0.0002709762,0.00139567],"study_design_scores_gemma":[0.00008201422,0.000271407,0.01209276,0.00003531103,0.00001170979,0.0005978249,0.00007202378,0.001408445,0.9751271,0.0001180507,0.01017515,0.000008151465],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9744635,0.005680805,0.007707155,0.0004887595,0.0002201023,0.0001144921,0.004832379,0.000281676,0.006211048],"genre_scores_gemma":[0.9640097,0.001273366,0.003760529,0.0001943679,0.00006009654,0.0001183442,0.0108573,0.00009770301,0.01962865],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00667228,"threshold_uncertainty_score":0.02232105,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1100327921167769,"score_gpt":0.378643068380715,"score_spread":0.2686102762639382,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}