{"id":"W2076012649","doi":"10.1097/yic.0b013e32835b09cd","title":"Safety and tolerability of duloxetine in elderly patients with major depressive disorder","year":2012,"lang":"en","type":"article","venue":"International Clinical Psychopharmacology","topic":"Treatment of Major Depression","field":"Medicine","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"Eli Lilly (Canada)","funders":"","keywords":"Duloxetine; Duloxetine Hydrochloride; Placebo; Tolerability; Adverse effect; Medicine; Internal medicine; Discontinuation; Nausea; Anesthesia","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002111756,0.0002604428,0.001112722,0.0002515458,0.0001928813,0.0003531419,0.0001626506,0.0003167273,0.0005574934],"category_scores_gemma":[0.003599594,0.0001366157,0.000861414,0.0002960113,0.0001618221,0.0002079228,0.0001426388,0.0003144433,0.0001008247],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002337847,"about_ca_system_score_gemma":0.0003273941,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006621185,"about_ca_topic_score_gemma":0.001756755,"domain_scores_codex":[0.9990255,0.0005427777,0.0001444593,0.00006753209,0.00017252,0.00004721582],"domain_scores_gemma":[0.9973521,0.0009985421,0.001168275,0.0000882808,0.0002403294,0.0001524963],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.1410571,0.001718709,0.5872378,0.003391718,0.008838371,0.0008968505,0.0003920012,0.0007104265,0.01738047,0.00007187798,0.001617148,0.2366875],"study_design_scores_gemma":[0.01022513,0.05822875,0.9215575,0.0001766851,0.004225265,0.001221334,0.0002300836,0.0006763042,0.001533002,0.00007324279,0.0018197,0.00003300301],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9800945,0.01833428,0.0002773008,0.0001687639,0.00004443536,0.0001038855,0.0003593796,0.00001252295,0.0006051018],"genre_scores_gemma":[0.9951701,0.003595037,0.0002829168,0.0003071938,0.0001420269,0.00005666285,0.0003132401,0.000002270806,0.0001305731],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002111756,"threshold_uncertainty_score":0.01116818,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02055853116773145,"score_gpt":0.3972388482432944,"score_spread":0.3766803170755629,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}