{"id":"W2076014057","doi":"10.1073/pnas.0804008105","title":"Netrin-4 inhibits angiogenesis via binding to neogenin and recruitment of Unc5B","year":2008,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Axon Guidance and Neuronal Signaling","field":"Neuroscience","cited_by":147,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Institute of Cancer Research; Retina France; Institut National Du Cancer; Centre National de la Recherche Scientifique","keywords":"Netrin; Angiogenesis; Matrigel; Receptor; Cell biology; Gene knockdown; Biology; Neovascularization; Axon guidance; Cancer research; Molecular biology; Biochemistry; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006412733,0.00009356373,0.0001604038,0.0002565956,0.0002640579,0.000008752996,0.0005165912,0.00004528054,0.000006264901],"category_scores_gemma":[0.0006813969,0.00006660593,0.00006463977,0.001397273,0.0006435472,0.0002942086,0.000201898,0.00007676167,0.000001687368],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000210737,"about_ca_system_score_gemma":0.00002811972,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004584452,"about_ca_topic_score_gemma":2.351135e-8,"domain_scores_codex":[0.9980462,0.000009725024,0.0003450027,0.000305063,0.001126837,0.0001671694],"domain_scores_gemma":[0.9992541,0.0002066355,0.000356995,0.00000791213,0.0001181716,0.00005616279],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000178856,0.0000235018,0.005094903,0.0000194411,0.000002372605,2.14766e-8,0.0001891507,0.00009124234,0.9898648,0.004064476,0.00009801429,0.0005341558],"study_design_scores_gemma":[0.0001045779,0.00008940679,0.01727313,0.00006561272,0.000005036102,0.00002961497,0.00003260013,0.0001833098,0.9802634,0.00174404,0.0001415763,0.00006774892],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9975156,0.0001032831,0.000002587866,0.001081,0.00001685904,0.000262873,0.0000101094,0.000008236859,0.0009994556],"genre_scores_gemma":[0.9985548,0.00008370615,0.0006906372,0.0005273845,0.00003470763,0.00001145401,1.752057e-8,0.000004274805,0.00009306306],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01217822,"threshold_uncertainty_score":0.2716111,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1932487585844073,"score_gpt":0.337888042480582,"score_spread":0.1446392838961747,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}