{"id":"W2076068934","doi":"10.1163/1568562054798563","title":"Polycarbonate-urethane hard segment type influences esterase substrate specificity for human-macrophage-mediated biodegradation","year":2005,"lang":"en","type":"article","venue":"Journal of Biomaterials Science Polymer Edition","topic":"biodegradable polymer synthesis and properties","field":"Materials Science","cited_by":41,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"","keywords":"Esterase; Phenylmethylsulfonyl Fluoride; PMSF; Chemistry; Biochemistry; Sodium fluoride; Butanediol; Substrate (aquarium); Molecular biology; Fluoride; Enzyme; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002878124,0.0003141559,0.0004981016,0.0004776314,0.0006425389,0.0007304474,0.0007170321,0.000148089,0.0006997156],"category_scores_gemma":[0.0001890505,0.0002289707,0.0001347921,0.0005450989,0.0008045072,0.00218449,0.00006342062,0.00007257149,0.00008690105],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001797713,"about_ca_system_score_gemma":0.0003651952,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001872619,"about_ca_topic_score_gemma":0.00001897814,"domain_scores_codex":[0.9964853,0.0001704362,0.001245342,0.0004414017,0.001027858,0.0006296968],"domain_scores_gemma":[0.9974894,0.0001223538,0.001189518,0.0002960193,0.0006134675,0.0002892248],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000354817,0.0001385811,0.0001130808,0.0000351169,0.0000135455,0.00000489453,0.0002422035,0.00000469185,0.9949999,0.0001188608,0.0002697033,0.003704629],"study_design_scores_gemma":[0.0006016286,0.0005002851,0.001388841,0.0001214973,0.00005457402,0.00006223306,0.0001439155,0.00008403086,0.9960951,0.0001454661,0.0005074223,0.0002950265],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9881562,0.00484652,0.0003474413,0.00122709,0.004891372,0.0002342794,0.0001962732,0.00005654758,0.00004425698],"genre_scores_gemma":[0.9953179,0.0001083564,0.002356586,0.0002085275,0.001865442,0.00001580615,0.00002588306,0.00002229138,0.00007920164],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007161687,"threshold_uncertainty_score":0.9337153,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03663832835642188,"score_gpt":0.2853119463482064,"score_spread":0.2486736179917846,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}