{"id":"W2076068934","doi":"10.1163/1568562054798563","title":"Polycarbonate-urethane hard segment type influences esterase substrate specificity for human-macrophage-mediated biodegradation","year":2005,"lang":"en","type":"article","venue":"Journal of Biomaterials Science Polymer Edition","topic":"biodegradable polymer synthesis and properties","field":"Materials Science","cited_by":41,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"","keywords":"Esterase; Phenylmethylsulfonyl Fluoride; PMSF; Chemistry; Biochemistry; Sodium fluoride; Butanediol; Substrate (aquarium); Molecular biology; Fluoride; Enzyme; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003406758,0.0003067542,0.0001514534,0.000108209,0.00008265504,0.0002039943,0.000107117,0.0002052743,0.001306649],"category_scores_gemma":[0.0004099686,0.000118106,0.0001618452,0.000112471,0.0001442967,0.0001421122,0.0001247422,0.0002079965,0.0002752943],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001177055,"about_ca_system_score_gemma":0.0001423659,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003918686,"about_ca_topic_score_gemma":0.0008752138,"domain_scores_codex":[0.9997175,0.00008690002,0.00003255663,0.00005456231,0.00005101549,0.00005743467],"domain_scores_gemma":[0.9997912,0.00009354569,0.00004011374,0.00001719846,0.0000331868,0.00002473443],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009979948,0.00001270762,0.0001102708,0.00001909271,0.000001176471,0.00001477191,0.000005753671,0.00001285582,0.9993398,0.000009734209,0.00000718028,0.0003668616],"study_design_scores_gemma":[0.000004271194,0.0001934345,0.001611818,0.000002190072,0.000004095758,0.00008413618,0.00000688886,0.0001357095,0.9973884,0.00000388702,0.0005631429,0.000002043537],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9963074,0.001262309,0.001313809,0.00002947006,0.00001965812,0.00002925712,0.0001069844,0.0000134591,0.0009176101],"genre_scores_gemma":[0.9956883,0.0007287497,0.002251905,0.00003413446,0.000008748758,0.00003291494,0.000212663,0.0000120365,0.001030536],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001306649,"threshold_uncertainty_score":0.004371166,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03663832835642188,"score_gpt":0.2853119463482064,"score_spread":0.2486736179917846,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}