{"id":"W2076129476","doi":"10.1152/ajpgi.00089.2010","title":"Oxidative stress enhances IL-8 and inhibits CCL20 production from intestinal epithelial cells in response to bacterial flagellin","year":2010,"lang":"en","type":"article","venue":"American Journal of Physiology-Gastrointestinal and Liver Physiology","topic":"Immune Response and Inflammation","field":"Immunology and Microbiology","cited_by":34,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research","keywords":"Flagellin; TLR5; CCL20; Cell biology; p38 mitogen-activated protein kinases; Chemokine; Interleukin 8; Innate immune system; Biology; Interleukin 22; Signal transduction; Oxidative stress; Kinase; Immune system; Protein kinase A; TLR4; Microbiology; Chemokine receptor; TLR2; Immunology; Inflammation; Receptor; Cytokine; Interleukin; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002266837,0.0005241143,0.0004958851,0.0002531897,0.0001809335,0.0004003809,0.0001582003,0.0003261676,0.001305223],"category_scores_gemma":[0.0001980524,0.0001966951,0.0004411425,0.0001641613,0.0002738799,0.000297752,0.0002654104,0.0004315634,0.0003361379],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003367694,"about_ca_system_score_gemma":0.0002354566,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006086688,"about_ca_topic_score_gemma":0.001022597,"domain_scores_codex":[0.9997012,0.00005469964,0.00002477125,0.00003802174,0.00006495111,0.000116264],"domain_scores_gemma":[0.9997702,0.00003000303,0.00006129525,0.00002478426,0.00003827161,0.00007547955],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004963483,0.00005465137,0.000265047,0.00005644866,0.000005439038,0.00005492689,0.00002370984,0.00002186938,0.9982791,0.00001325193,0.00004390276,0.0006852567],"study_design_scores_gemma":[0.00011179,0.001704622,0.03091235,0.00002122501,0.00003027219,0.0002530281,0.0001271159,0.0006915244,0.9634919,0.00005477134,0.002589718,0.00001175163],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9952543,0.002983336,0.0005475869,0.0001284489,0.00006018391,0.00003074749,0.0002099167,0.00003709281,0.0007484432],"genre_scores_gemma":[0.9960079,0.001196075,0.0006021475,0.0001413606,0.00005384169,0.00006405406,0.0003974111,0.000008969234,0.001528175],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001305223,"threshold_uncertainty_score":0.004366398,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005054568755966181,"score_gpt":0.2120876941301693,"score_spread":0.2070331253742031,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}