{"id":"W2076139670","doi":"10.1371/journal.pone.0004912","title":"Serum Angiopoietin-1 and -2 Levels Discriminate Cerebral Malaria from Uncomplicated Malaria and Predict Clinical Outcome in African Children","year":2009,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Malaria Research and Control","field":"Medicine","cited_by":202,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; University Health Network; Centre for Global Health Research","funders":"Fogarty International Center; Canada Research Chairs; National Institutes of Health; Canadian Institutes of Health Research; Genome Canada; Ontario Genomics; Ontario Genomics Institute","keywords":"Malaria; Angiopoietin 2; Cerebral Malaria; Plasmodium falciparum; Medicine; Receiver operating characteristic; Angiopoietin; Pathogenesis; Internal medicine; Immunology; Population; Endothelial activation; Gastroenterology; Vascular endothelial growth factor; Endothelium","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005738026,0.0002494818,0.0008113839,0.0001507928,0.00006805139,0.00006664741,0.0001677789,0.0002131852,0.0002612369],"category_scores_gemma":[0.0004801535,0.0002087168,0.00008232331,0.0001967131,0.0001583006,0.0001210943,0.0001344272,0.0006848985,0.00002206119],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003827726,"about_ca_system_score_gemma":0.00006601942,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003174358,"about_ca_topic_score_gemma":0.00007087515,"domain_scores_codex":[0.9975396,0.0002027419,0.0006309215,0.0006143441,0.0004557177,0.0005566937],"domain_scores_gemma":[0.9986671,0.0001736133,0.000100999,0.0004529013,0.00007472077,0.0005307292],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0008602713,0.001511399,0.9897063,0.00003813695,0.000344004,0.00006713604,0.0001000583,1.012058e-7,0.003359596,0.0009538163,0.00009751795,0.002961713],"study_design_scores_gemma":[0.006913842,0.0009010774,0.9886152,0.0001736981,0.0003442581,0.00001419126,0.00003927112,0.00102996,0.0002936475,0.001463949,0.000009431042,0.0002015422],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9479468,0.0003115239,0.00003011587,0.0492957,0.00001882666,0.001085105,0.0002377612,0.00008492087,0.0009891887],"genre_scores_gemma":[0.9963167,0.00005843981,0.001881043,0.0008190035,0.0002520943,0.00002616719,0.00009238666,0.00002598772,0.0005281537],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0484767,"threshold_uncertainty_score":0.8511224,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07974201828014123,"score_gpt":0.3115243444333999,"score_spread":0.2317823261532587,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}