{"id":"W2076190832","doi":"10.4021/wjon2010.03.195w","title":"Sesamin Induces Human Leukemic Cell Apoptosis via Mitochondrial and Endoplasmic Reticulum Stress Pathways","year":2010,"lang":"en","type":"article","venue":"World Journal of Oncology","topic":"Sesame and Sesamin Research","field":"Agricultural and Biological Sciences","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Chiang Mai University","keywords":"Sesamin; Apoptosis; Endoplasmic reticulum; Reactive oxygen species; Cytochrome c; Oxidative stress; Unfolded protein response; Cell biology; Molecular biology; Chemistry; Biochemistry; Biology","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003939556,0.0001589378,0.0003728053,0.00008721935,0.0002417987,0.00007194699,0.0004210629,0.0001917971,0.0007036069],"category_scores_gemma":[0.00008861605,0.00006561784,0.0001219359,0.0002808377,0.0002269409,0.0001449345,0.000114873,0.0009281543,0.00001509426],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004576885,"about_ca_system_score_gemma":0.00006479052,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001751821,"about_ca_topic_score_gemma":0.002858885,"domain_scores_codex":[0.9984376,0.0001957203,0.0004627167,0.0002202209,0.0003097212,0.0003740095],"domain_scores_gemma":[0.9985399,0.0006307379,0.0003439055,0.00006399407,0.0001763707,0.0002451433],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006618817,0.0001830614,0.004575721,0.000005086202,0.00001570322,0.00003817899,0.0001121988,7.891067e-7,0.9478714,0.00008083483,0.001418533,0.04563231],"study_design_scores_gemma":[0.001989728,0.004466676,0.0828852,0.00005030754,0.00007617299,0.0004679159,0.001219098,0.00002587029,0.8109862,0.00124745,0.09615184,0.0004335193],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9946294,0.0001393911,0.000001314237,0.001076106,0.000960986,0.0001243857,0.00001287029,0.00001194534,0.003043638],"genre_scores_gemma":[0.9973035,0.0001107377,0.0003675098,0.000169677,0.001470751,0.000004984016,0.000007997854,0.00000199307,0.0005628184],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1368852,"threshold_uncertainty_score":0.7704002,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02570702087520499,"score_gpt":0.2709662845653383,"score_spread":0.2452592636901333,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}