{"id":"W2076197944","doi":"10.4161/cc.9.19.13563","title":"A dynamic methylome: Implications of non-CG methylation/demethylation","year":2010,"lang":"en","type":"letter","venue":"Cell Cycle","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Cancer Institute; Canadian Institutes of Health Research; McGill University","keywords":"Biology; DNA methylation; Methylation; Demethylation; Epigenetics; Epigenomics; Computational biology; Genetics; Gene; Gene expression","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0003888884,0.0003470725,0.0003775158,0.0002055806,0.000113552,0.0000317644,0.0004208589,0.002174124,0.00008673704],"category_scores_gemma":[0.0001023477,0.0003682224,0.0002774663,0.0002312012,0.000120313,0.000006277586,0.0001349914,0.001170993,0.00003561944],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002841606,"about_ca_system_score_gemma":0.000169951,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004042894,"about_ca_topic_score_gemma":0.00004193246,"domain_scores_codex":[0.9980102,0.0001272693,0.0006129183,0.0006437826,0.00026559,0.0003402784],"domain_scores_gemma":[0.9978608,0.00008544234,0.0005781638,0.001073785,0.0003295771,0.00007219295],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000006818544,0.00003947892,0.0001477694,0.0001009693,0.00004754709,9.715829e-7,0.0000342102,0.0002047736,0.9703676,0.000004064836,0.02504781,0.00399801],"study_design_scores_gemma":[0.0003200718,0.0001314992,0.002931576,0.00001262594,0.0001138889,0.000001076583,0.00000727201,0.000398418,0.6053466,0.00155646,0.3887689,0.0004116588],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7260513,0.009214103,0.1112119,0.1145218,0.002185492,0.002472145,0.0008242839,0.00009693646,0.03342202],"genre_scores_gemma":[0.9335802,0.001289142,0.0179553,0.02903944,0.001993696,0.0001995377,0.009739737,0.0002608713,0.005942067],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.365021,"threshold_uncertainty_score":0.999877,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007418673235210648,"score_gpt":0.2629247667294938,"score_spread":0.2555060934942832,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}