{"id":"W2076280915","doi":"10.1165/rcmb.2006-0184tr","title":"Cystic Fibrosis Mouse Models","year":2006,"lang":"en","type":"review","venue":"American Journal of Respiratory Cell and Molecular Biology","topic":"Cystic Fibrosis Research Advances","field":"Medicine","cited_by":237,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto General Hospital; University of Toronto; McGill University; University Health Network","funders":"","keywords":"Cystic fibrosis; Genetically modified mouse; Knockout mouse; Transgene; Animal model; Human disease; Phenotype; Biology; Disease; Model organism; Computational biology; Pathogenesis; Laboratory mouse; Genetically engineered; Inbred strain; Neuroscience; Bioinformatics; Immunology; Medicine; Genetics; Gene; Pathology; Endocrinology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008838258,0.001272106,0.001577213,0.002595772,0.0003733738,0.000840267,0.001639302,0.001260674,0.005118258],"category_scores_gemma":[0.0005715643,0.000265618,0.000463744,0.00139211,0.0004139295,0.0008563673,0.0006331604,0.001445583,0.007353647],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003864335,"about_ca_system_score_gemma":0.0004845832,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006104559,"about_ca_topic_score_gemma":0.001130568,"domain_scores_codex":[0.9996011,0.0000649894,0.00004117499,0.00005778849,0.0001992087,0.00003575497],"domain_scores_gemma":[0.9997268,0.00007469163,0.00004895053,0.00001870865,0.00007948562,0.0000512781],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000166011,0.0002452054,0.0004918636,0.01029749,0.00007068776,0.001394583,0.0001299105,0.0004985803,0.07344728,0.008913102,0.0931172,0.8112281],"study_design_scores_gemma":[0.00002186972,0.0001202197,0.0006003972,0.0007817915,0.00005170209,0.003101278,0.00002793948,0.00007308073,0.00530529,0.00124882,0.9886476,0.00002002263],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00177952,0.967806,0.00798797,0.000801979,0.00121847,0.0002145568,0.0006921044,0.000356049,0.01914336],"genre_scores_gemma":[0.00489039,0.9712648,0.00897974,0.0007737499,0.0003392807,0.0002664372,0.001278888,0.00003383072,0.01217294],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.005118258,"threshold_uncertainty_score":0.01712227,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02273252780896415,"score_gpt":0.342173255372231,"score_spread":0.3194407275632668,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}