{"id":"W2076280915","doi":"10.1165/rcmb.2006-0184tr","title":"Cystic Fibrosis Mouse Models","year":2006,"lang":"en","type":"review","venue":"American Journal of Respiratory Cell and Molecular Biology","topic":"Cystic Fibrosis Research Advances","field":"Medicine","cited_by":237,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto General Hospital; University of Toronto; McGill University; University Health Network","funders":"","keywords":"Cystic fibrosis; Genetically modified mouse; Knockout mouse; Transgene; Animal model; Human disease; Phenotype; Biology; Disease; Model organism; Computational biology; Pathogenesis; Laboratory mouse; Genetically engineered; Inbred strain; Neuroscience; Bioinformatics; Immunology; Medicine; Genetics; Gene; Pathology; Endocrinology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003945914,0.0004142094,0.002532037,0.0005685036,0.00004756303,0.00002221841,0.000254735,0.0001905471,0.00001297881],"category_scores_gemma":[0.0001476756,0.0002888266,0.0006210383,0.0003562284,0.0007845815,0.00004975587,0.0001063091,0.0007086575,0.000007847178],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001052798,"about_ca_system_score_gemma":0.0008006357,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002300779,"about_ca_topic_score_gemma":8.831103e-7,"domain_scores_codex":[0.997402,0.0005498648,0.0009601797,0.0003712658,0.0002773387,0.0004393941],"domain_scores_gemma":[0.9976317,0.0002881179,0.001104095,0.0003582377,0.0002302202,0.0003876327],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001358091,0.00009399379,0.000008978584,0.003374298,0.0002243725,0.0004336791,0.000008020044,0.00001082142,0.007102792,0.00006137688,0.0005423793,0.9880035],"study_design_scores_gemma":[0.0005110207,0.004538875,0.000001217409,0.001768411,0.0007905219,0.0005860971,0.00001828615,0.000005575255,0.0003679869,0.0001189942,0.9910342,0.000258837],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001060013,0.9917072,0.006408756,0.00001947784,0.00006820609,0.0003089849,0.00004778903,0.00001179442,0.0003677436],"genre_scores_gemma":[0.0003625266,0.9911217,0.007830116,0.0002747686,0.0001881855,0.00001469485,0.00002730512,0.00007091073,0.0001097706],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9904918,"threshold_uncertainty_score":0.9999564,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02273252780896415,"score_gpt":0.342173255372231,"score_spread":0.3194407275632668,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}