{"id":"W2076282325","doi":"10.1021/ja310718f","title":"Enantioselective Formal Aza-Diels–Alder Reactions of Enones with Cyclic Imines Catalyzed by Primary Aminothioureas","year":2013,"lang":"en","type":"article","venue":"Journal of the American Chemical Society","topic":"Asymmetric Synthesis and Catalysis","field":"Chemistry","cited_by":151,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of General Medical Sciences; Natural Sciences and Engineering Research Council of Canada","keywords":"Chemistry; Imine; Bifunctional; Enantioselective synthesis; Enone; Catalysis; Organic chemistry; Combinatorial chemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000337644,0.0007175985,0.0002975358,0.0003025052,0.0001744758,0.0002819472,0.000405471,0.0002094293,0.001436009],"category_scores_gemma":[0.0002243156,0.0001454566,0.0002220123,0.0001476224,0.0003638704,0.0003230063,0.0003567092,0.0005214767,0.0004839482],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004724902,"about_ca_system_score_gemma":0.0003711304,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006759891,"about_ca_topic_score_gemma":0.001736734,"domain_scores_codex":[0.9998161,0.00002970557,0.00002011133,0.00002310433,0.00004548591,0.00006543734],"domain_scores_gemma":[0.9999253,0.00001340095,0.00001699731,0.00001281015,0.00001434105,0.00001714577],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001085517,0.00005518888,0.0002440062,0.0002230309,0.00002331579,0.0005374771,0.0001810352,0.001233458,0.9775213,0.007346905,0.0002907014,0.01223497],"study_design_scores_gemma":[0.00002683342,0.0002456093,0.0004379683,0.000008737461,0.00001455518,0.0003302766,0.00002382243,0.001041726,0.9912128,0.0004076449,0.006233425,0.00001669048],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9197658,0.004391697,0.04734575,0.0003211296,0.0002368696,0.0001801568,0.0005097497,0.0004975811,0.02675127],"genre_scores_gemma":[0.9846497,0.001436049,0.01001948,0.00003156627,0.00002001204,0.0000418946,0.0002071948,0.0000251526,0.003569067],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001436009,"threshold_uncertainty_score":0.004803896,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004458045510263428,"score_gpt":0.201343231373404,"score_spread":0.1968851858631406,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}