{"id":"W2076312642","doi":"10.1158/1538-7445.tim2013-a9","title":"Abstract A9: Immune suppressive myeloid cells induced by hypoxic mammary tumor cells persist after primary tumor resection and promote metastatic growth","year":2013,"lang":"en","type":"article","venue":"Cancer Research","topic":"Immune cells in cancer","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Cancer Agency","funders":"","keywords":"Cancer research; Immune system; Tirapazamine; Mammary tumor; Primary tumor; Myeloid-derived Suppressor Cell; Biology; Spleen; Metastasis; Myeloid; Tumor progression; Integrin alpha M; In vivo; Tumor hypoxia; Tumor microenvironment; Immunology; Medicine; Cancer; In vitro; Breast cancer; Suppressor; Internal medicine; Cytotoxicity; Radiation therapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008400925,0.000233269,0.00022634,0.0001977148,0.0001206709,0.0001915803,0.00008741326,0.0001770118,0.003609391],"category_scores_gemma":[0.00006023547,0.00006925947,0.0001800951,0.0001034956,0.0001575342,0.0001149721,0.0001620847,0.0005441059,0.0008799474],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002016826,"about_ca_system_score_gemma":0.0001692498,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000397168,"about_ca_topic_score_gemma":0.0003632126,"domain_scores_codex":[0.9999079,0.000008355938,0.000006830522,0.00001801119,0.00002442982,0.00003449293],"domain_scores_gemma":[0.9998652,0.00001652925,0.00002941143,0.00001540733,0.00001716958,0.00005632399],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001059083,0.00003329136,0.0002288063,0.00001351925,0.000001396259,0.0000319016,0.000006234856,0.00001593062,0.9986662,0.00007198755,0.00006635391,0.0007583852],"study_design_scores_gemma":[0.0000219365,0.0006504227,0.007349521,0.000004713489,0.00000751467,0.000254434,0.00003158217,0.0004828012,0.9887166,0.00006893741,0.002409497,0.000002003521],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9940202,0.0006234325,0.00220188,0.0001087992,0.00003351027,0.00003740663,0.0008981623,0.0001151794,0.001961505],"genre_scores_gemma":[0.9906069,0.0003096329,0.001358839,0.00007164761,0.00002786457,0.00005203391,0.001018945,0.00003165958,0.006522507],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003609391,"threshold_uncertainty_score":0.01207459,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02155657260515477,"score_gpt":0.2852144963211555,"score_spread":0.2636579237160007,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}