{"id":"W2076338583","doi":"10.1006/jmcc.2000.1192","title":"Interactions of Dynorphin A-(1–13) and Nociceptin with Cardiac D2 Binding Sites: Inhibition of Ischemia-evoked Release of Noradrenaline from Synaptosomal–mitochondrial Fractions","year":2000,"lang":"en","type":"article","venue":"Journal of Molecular and Cellular Cardiology","topic":"Neuropeptides and Animal Physiology","field":"Neuroscience","cited_by":6,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Ottawa","funders":"","keywords":"Nociceptin receptor; Raclopride; Chemistry; Rauwolscine; Dynorphin A; Binding site; Sulpiride; Receptor; Antagonist; Stereochemistry; Biochemistry; Prazosin; Opioid peptide; Opioid","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003732768,0.0004416392,0.000487148,0.0002424029,0.0004782453,0.0002930399,0.0006205134,0.0004138267,0.002474161],"category_scores_gemma":[0.0003602528,0.0003853597,0.0004498571,0.0002015021,0.0004542306,0.0003894164,0.0003481947,0.0007683321,0.0004493032],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007678472,"about_ca_system_score_gemma":0.0004898417,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003140833,"about_ca_topic_score_gemma":0.00522752,"domain_scores_codex":[0.9997079,0.00005115629,0.00001656054,0.00004032402,0.00002951584,0.0001544393],"domain_scores_gemma":[0.9996853,0.0001207426,0.0000402211,0.00002543045,0.00001940191,0.0001088085],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002268645,0.0001019171,0.0001740711,0.00006372744,0.00002902153,0.0001096898,0.00004924616,0.0001386585,0.9961025,0.0001434384,0.00005094846,0.0007682456],"study_design_scores_gemma":[0.000135894,0.0008195965,0.006758301,0.000008556072,0.00004318606,0.000243561,0.0000578624,0.001845237,0.9893094,0.00008066733,0.0006855791,0.00001223326],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9970601,0.001091825,0.0008342649,0.00004885046,0.00001720296,0.00002416872,0.0001193873,0.00001465995,0.0007895069],"genre_scores_gemma":[0.9963986,0.0006588316,0.0009764569,0.000029118,0.00001488707,0.00003486916,0.0002827012,0.000009127117,0.001595468],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003140833,"threshold_uncertainty_score":0.00827688,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01146133994151102,"score_gpt":0.2227098484152963,"score_spread":0.2112485084737853,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}