{"id":"W2076341925","doi":"10.1016/j.ijrobp.2012.09.023","title":"RTOG 0529: A Phase 2 Evaluation of Dose-Painted Intensity Modulated Radiation Therapy in Combination With 5-Fluorouracil and Mitomycin-C for the Reduction of Acute Morbidity in Carcinoma of the Anal Canal","year":2012,"lang":"en","type":"article","venue":"International Journal of Radiation Oncology*Biology*Physics","topic":"Colorectal and Anal Carcinomas","field":"Medicine","cited_by":624,"is_retracted":false,"has_abstract":false,"ca_institutions":"Dalhousie University","funders":"National Cancer Institute","keywords":"Medicine; Anal cancer; Clinical endpoint; Genitourinary system; Radiation therapy; Anal canal; Anal Carcinoma; Phases of clinical research; Mitomycin C; Adverse effect; Nuclear medicine; Fluorouracil; Urology; Cancer; Oncology; Internal medicine; Chemotherapy; Surgery; Randomized controlled trial; Rectum","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001799588,0.0001308099,0.0004239048,0.0002284769,0.00003725516,0.00000458409,0.00015604,0.0001377957,0.000009354226],"category_scores_gemma":[0.0002804134,0.00008324838,0.0001384374,0.0003516466,0.0002005387,0.0002292345,0.0000255581,0.0002900735,1.001693e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005442319,"about_ca_system_score_gemma":0.0005144719,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005834688,"about_ca_topic_score_gemma":0.0001088357,"domain_scores_codex":[0.9982427,0.0003398112,0.0007273311,0.0001282016,0.0004211737,0.0001408331],"domain_scores_gemma":[0.9964973,0.000269558,0.001304608,0.000115315,0.001765559,0.00004766332],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.005547819,0.001089377,0.872504,0.00001770954,0.0004650645,0.000001312942,0.00190908,0.0009980476,0.03353066,0.0006027084,0.00005022034,0.08328402],"study_design_scores_gemma":[0.01454489,0.002035337,0.9157205,0.00005594428,0.000346228,0.0001011911,0.0002737314,0.03727864,0.02841352,0.00112213,0.00003508788,0.00007276505],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9962441,0.0004996287,0.0006448291,0.001301654,0.0006049116,0.0006337078,0.00004951641,0.000003323321,0.00001828412],"genre_scores_gemma":[0.9991209,0.0002173772,0.0001686111,0.00006113439,0.0003358459,0.00001680995,0.00006594016,0.00000994041,0.000003421329],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.08321125,"threshold_uncertainty_score":0.339477,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04184106476874297,"score_gpt":0.3497193537737751,"score_spread":0.3078782890050321,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}