{"id":"W2076341925","doi":"10.1016/j.ijrobp.2012.09.023","title":"RTOG 0529: A Phase 2 Evaluation of Dose-Painted Intensity Modulated Radiation Therapy in Combination With 5-Fluorouracil and Mitomycin-C for the Reduction of Acute Morbidity in Carcinoma of the Anal Canal","year":2012,"lang":"en","type":"article","venue":"International Journal of Radiation Oncology*Biology*Physics","topic":"Colorectal and Anal Carcinomas","field":"Medicine","cited_by":624,"is_retracted":false,"has_abstract":false,"ca_institutions":"Dalhousie University","funders":"National Cancer Institute","keywords":"Medicine; Anal cancer; Clinical endpoint; Genitourinary system; Radiation therapy; Anal canal; Anal Carcinoma; Phases of clinical research; Mitomycin C; Adverse effect; Nuclear medicine; Fluorouracil; Urology; Cancer; Oncology; Internal medicine; Chemotherapy; Surgery; Randomized controlled trial; Rectum","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00239792,0.001999923,0.002129619,0.0008655495,0.0005243194,0.001111798,0.001871481,0.002032867,0.004558149],"category_scores_gemma":[0.001094076,0.0008242072,0.001773539,0.0006416261,0.00132099,0.000870107,0.000511924,0.003158589,0.001122263],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001144774,"about_ca_system_score_gemma":0.002858838,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003947963,"about_ca_topic_score_gemma":0.007797673,"domain_scores_codex":[0.9993731,0.0003395045,0.00002427629,0.00008067785,0.000062827,0.0001196167],"domain_scores_gemma":[0.9994504,0.00009185037,0.0001020514,0.00005088662,0.00003843931,0.000266234],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.5666065,0.1821811,0.00577275,0.001513622,0.001819866,0.0003614985,0.0007991178,0.0101226,0.08613003,0.0009908407,0.005905503,0.1377966],"study_design_scores_gemma":[0.4661243,0.5139193,0.007020713,0.00005829769,0.0005496292,0.0003012735,0.00008949883,0.002096434,0.006603291,0.0002033582,0.002991695,0.00004225881],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9899825,0.001608477,0.0008555772,0.0004769431,0.0001214726,0.003618847,0.001424061,0.0001633261,0.001748909],"genre_scores_gemma":[0.9705997,0.004135048,0.00699765,0.001584136,0.0002200914,0.006252326,0.004907535,0.0001216502,0.005181788],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004558149,"threshold_uncertainty_score":0.01524854,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04184106476874297,"score_gpt":0.3497193537737751,"score_spread":0.3078782890050321,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}