{"id":"W2076393638","doi":"10.1021/ja030669g","title":"The<i>N</i>-Acyloxyiminium Ion Aza-Prins Route to Octahydroindoles:  Total Synthesis and Structural Confirmation of the Antithrombotic Marine Natural Product Oscillarin","year":2004,"lang":"en","type":"article","venue":"Journal of the American Chemical Society","topic":"Marine Sponges and Natural Products","field":"Biochemistry, Genetics and Molecular Biology","cited_by":134,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"","keywords":"Chemistry; Enantiopure drug; Iminium; Natural product; Stereochemistry; Total synthesis; Alkene; Crystal structure; Carbocation; Ion; Organic chemistry; Enantioselective synthesis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001131335,0.0003746226,0.0001958826,0.0001744673,0.0001029502,0.0001831218,0.0003356105,0.0001421651,0.0009731209],"category_scores_gemma":[0.0001398163,0.0001200158,0.0002006889,0.0001389462,0.0001911562,0.0001957208,0.000318308,0.0003995938,0.0006454502],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001904938,"about_ca_system_score_gemma":0.0002576804,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003090167,"about_ca_topic_score_gemma":0.0004642159,"domain_scores_codex":[0.9999301,0.00001353672,0.000005705354,0.00001460282,0.0000161005,0.00001987139],"domain_scores_gemma":[0.9999338,0.000007938657,0.00001837595,0.00001147713,0.00001152356,0.00001679188],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009002705,0.00001892958,0.000141899,0.0001069865,0.00001215082,0.0003002207,0.0000704486,0.0003455516,0.9819214,0.001353507,0.0001739681,0.01546484],"study_design_scores_gemma":[0.00002082268,0.0005236851,0.00102202,0.00000903942,0.00002215629,0.0008695406,0.00002787773,0.0006707604,0.984349,0.0004410186,0.01203045,0.0000136229],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8653076,0.004396041,0.1054304,0.0003960773,0.000123754,0.0001823403,0.0007633209,0.0005290144,0.02287145],"genre_scores_gemma":[0.957891,0.002438449,0.03344864,0.00007350058,0.00002133287,0.00005593224,0.000469325,0.0000817459,0.00552002],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009731209,"threshold_uncertainty_score":0.003255486,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004209646571010952,"score_gpt":0.2260449558724342,"score_spread":0.2218353093014233,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}