{"id":"W2076407990","doi":"10.1002/stem.462","title":"<i>Bmi1</i> Distinguishes Immature Retinal Progenitor/Stem Cells from the Main Progenitor Cell Population and Is Required for Normal Retinal Development  ","year":2010,"lang":"en","type":"article","venue":"Stem Cells","topic":"Retinal Development and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":29,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Hôpital Maisonneuve-Rosemont","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Biology; BMI1; Neurosphere; Progenitor cell; Cell biology; SOX2; Stem cell; Retinal; Embryonic stem cell; Retina; Neural stem cell; Population; Immunology; Adult stem cell; Genetics; Neuroscience","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008405637,0.0002983647,0.0001635402,0.0003644104,0.0001560685,0.0003807912,0.000165547,0.0001774051,0.002235496],"category_scores_gemma":[0.000111179,0.0001269556,0.0001392418,0.0001630226,0.0002414654,0.0001938668,0.0001962597,0.0005262784,0.001020564],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002252567,"about_ca_system_score_gemma":0.0001560816,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008169973,"about_ca_topic_score_gemma":0.0006979546,"domain_scores_codex":[0.9999093,0.000008629472,0.00001252899,0.00002212444,0.00003151104,0.00001601297],"domain_scores_gemma":[0.9998698,0.00001024908,0.00005878726,0.00001225361,0.00001477178,0.00003413773],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004088901,0.000005006088,0.0003713177,0.00002049077,0.00000118764,0.00002110402,0.000004619321,0.00001676802,0.9979911,0.00009347438,0.00004180512,0.001392319],"study_design_scores_gemma":[0.00000990116,0.0001183928,0.01956505,0.00001243326,0.00001148016,0.00084331,0.00002185381,0.0005462254,0.9728534,0.00009165696,0.005919151,0.000007167184],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9758009,0.005584883,0.0107729,0.0002924312,0.00007757121,0.00005868256,0.002613734,0.0004607231,0.004338228],"genre_scores_gemma":[0.9785118,0.002902511,0.008143143,0.0001048191,0.00004354991,0.00007789865,0.004492634,0.0001298552,0.005593915],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002235496,"threshold_uncertainty_score":0.007478476,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007064294149697754,"score_gpt":0.2094488081205669,"score_spread":0.2023845139708692,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}