{"id":"W2076407990","doi":"10.1002/stem.462","title":"<i>Bmi1</i> Distinguishes Immature Retinal Progenitor/Stem Cells from the Main Progenitor Cell Population and Is Required for Normal Retinal Development  ","year":2010,"lang":"en","type":"article","venue":"Stem Cells","topic":"Retinal Development and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":29,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Hôpital Maisonneuve-Rosemont","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Biology; BMI1; Neurosphere; Progenitor cell; Cell biology; SOX2; Stem cell; Retinal; Embryonic stem cell; Retina; Neural stem cell; Population; Immunology; Adult stem cell; Genetics; Neuroscience","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003832166,0.0003346117,0.0002184254,0.00002502333,0.0003714662,0.0001345594,0.0003161064,0.0003040227,0.00001936127],"category_scores_gemma":[0.0000126792,0.0002611416,0.0001136253,0.0000823865,0.00009515408,0.00001202501,0.0001609629,0.0002023546,0.0000157524],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001899129,"about_ca_system_score_gemma":0.0001460615,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003174724,"about_ca_topic_score_gemma":0.0000833287,"domain_scores_codex":[0.9981546,0.00006960361,0.0004432185,0.0006156697,0.0002694017,0.0004474382],"domain_scores_gemma":[0.9990807,0.00005433402,0.0002516805,0.0003490942,0.0001292879,0.0001348586],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00055409,0.00005682442,0.01904489,0.0001165224,0.00004837413,0.000003760421,0.0006313451,9.378363e-7,0.9646043,0.00001488119,0.009522752,0.005401384],"study_design_scores_gemma":[0.0006917242,0.0001184008,0.005706093,0.00003346548,0.00004284266,0.000007717907,0.0004426451,0.00002073535,0.8781133,0.00004104959,0.1143869,0.0003950859],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9965199,0.0005240466,0.000207176,0.0001961522,0.0008420952,0.001015421,0.0001193678,0.0000262623,0.0005495688],"genre_scores_gemma":[0.9879175,0.00004053645,0.007464686,0.000209704,0.0007268802,0.0001392734,0.0003371075,0.00005343759,0.003110894],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1048642,"threshold_uncertainty_score":0.9999841,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007064294149697754,"score_gpt":0.2094488081205669,"score_spread":0.2023845139708692,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}