{"id":"W2076430862","doi":"10.1016/j.bbadis.2005.05.001","title":"The healing rabbit medial collateral ligament of the knee responds to systemically administered glucocorticoids differently than the uninjured tissues of the same joint or the uninjured MCL: A paradoxical shift in impact on specific mRNA levels and MMP-13 protein expression in injured tissues","year":2005,"lang":"en","type":"article","venue":"Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease","topic":"Tendon Structure and Treatment","field":"Medicine","cited_by":19,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Calgary","funders":"Institute of Gender and Health; Canadian Institutes of Health Research; Arthritis Society; National Institute for Health and Care Research; Calgary Foundation","keywords":"Connective tissue; Glucocorticoid receptor; Glucocorticoid; Biglycan; In vivo; Medial collateral ligament; Biology; Inflammation; Granulation tissue; Endocrinology; Decorin; Wound healing; Internal medicine; Pathology; Medicine; Extracellular matrix; Cell biology; Immunology; Ligament; Anatomy; Proteoglycan","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002406298,0.0003591904,0.0005094308,0.0003234828,0.0002291676,0.0004629733,0.0001729391,0.000403798,0.001136437],"category_scores_gemma":[0.000283675,0.0003133699,0.0003467022,0.0002534532,0.0006487757,0.0004084249,0.0001901865,0.0006479396,0.0003435629],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002771129,"about_ca_system_score_gemma":0.0002879034,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001034447,"about_ca_topic_score_gemma":0.002064227,"domain_scores_codex":[0.9996809,0.0000555402,0.00002631778,0.00005607807,0.00006526882,0.0001158499],"domain_scores_gemma":[0.9996674,0.00007122733,0.00007676383,0.00005998092,0.00003055648,0.00009413421],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003268622,0.00001499679,0.0001654712,0.00002066774,0.00000220829,0.00004908188,0.0000174816,0.000007896148,0.9990824,0.00002449314,0.000006949868,0.0002814701],"study_design_scores_gemma":[0.00005330795,0.00176277,0.01941749,0.00001189074,0.00004653084,0.0005195662,0.000343081,0.000300787,0.9766674,0.00008901769,0.0007784587,0.000009666534],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9964245,0.001829007,0.0005330803,0.00007776681,0.00004437921,0.00001124406,0.000119025,0.00002355874,0.0009373373],"genre_scores_gemma":[0.9965491,0.0009091334,0.0006233684,0.00007844384,0.00002715586,0.00002061978,0.0001749128,0.0000145312,0.001602535],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001136437,"threshold_uncertainty_score":0.003801823,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01822335255150151,"score_gpt":0.294098951165047,"score_spread":0.2758755986135455,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}