{"id":"W2076430862","doi":"10.1016/j.bbadis.2005.05.001","title":"The healing rabbit medial collateral ligament of the knee responds to systemically administered glucocorticoids differently than the uninjured tissues of the same joint or the uninjured MCL: A paradoxical shift in impact on specific mRNA levels and MMP-13 protein expression in injured tissues","year":2005,"lang":"en","type":"article","venue":"Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease","topic":"Tendon Structure and Treatment","field":"Medicine","cited_by":19,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Calgary","funders":"Institute of Gender and Health; Canadian Institutes of Health Research; Arthritis Society; National Institute for Health and Care Research; Calgary Foundation","keywords":"Connective tissue; Glucocorticoid receptor; Glucocorticoid; Biglycan; In vivo; Medial collateral ligament; Biology; Inflammation; Granulation tissue; Endocrinology; Decorin; Wound healing; Internal medicine; Pathology; Medicine; Extracellular matrix; Cell biology; Immunology; Ligament; Anatomy; Proteoglycan","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003770764,0.0005191661,0.0009003123,0.0001586713,0.0001565191,0.00006946854,0.0006620233,0.0001414996,0.00001003551],"category_scores_gemma":[0.000249399,0.0001861053,0.0004613374,0.000631291,0.0005381633,0.00005151713,0.0003665327,0.0003795746,9.195033e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001614538,"about_ca_system_score_gemma":0.0003803901,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001026358,"about_ca_topic_score_gemma":0.00008556699,"domain_scores_codex":[0.9958113,0.00106425,0.001099862,0.0005444307,0.001013082,0.0004670698],"domain_scores_gemma":[0.9972184,0.00030212,0.0005875341,0.001513799,0.00008981056,0.0002883881],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.01503603,0.0009046312,0.0006278571,0.0001388854,0.0002207627,0.00001753844,0.002984977,0.00001459875,0.9786941,0.0001577297,0.000048892,0.001153996],"study_design_scores_gemma":[0.002204599,0.001174808,0.3121469,0.001677185,0.0001872927,0.000003907177,0.0002577303,0.00002626939,0.6819226,0.0002023636,0.00003571122,0.0001605991],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9708095,0.000582661,0.000003648928,0.02456738,0.000082892,0.003655964,0.0002706323,0.00001754947,0.000009754843],"genre_scores_gemma":[0.9990956,0.00006236182,0.0001038353,0.0002991509,0.00009795516,0.0002405964,0.00001466711,0.00005220008,0.00003362535],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3115191,"threshold_uncertainty_score":0.7589153,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01822335255150151,"score_gpt":0.294098951165047,"score_spread":0.2758755986135455,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}