{"id":"W2076433016","doi":"10.1242/jcs.087395","title":"Cadherin Point Mutations Alter Cell Sorting and Modulate GTPase Signaling","year":2012,"lang":"en","type":"article","venue":"Journal of Cell Science","topic":"Hippo pathway signaling and YAP/TAZ","field":"Biochemistry, Genetics and Molecular Biology","cited_by":23,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Heart, Lung, and Blood Institute; McMaster University","keywords":"Biology; Cadherin; Cell biology; Point mutation; GTPase; Sorting; Signal transduction; Cell; Genetics; Mutation; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001539308,0.0005091164,0.0003248593,0.0002732596,0.0001920156,0.0004132779,0.0002838379,0.000540941,0.001669248],"category_scores_gemma":[0.0002830869,0.0002243883,0.0002013982,0.0001866371,0.000300482,0.0002468777,0.0002683866,0.0006400833,0.0003082881],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003947818,"about_ca_system_score_gemma":0.0001683761,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006652051,"about_ca_topic_score_gemma":0.00140696,"domain_scores_codex":[0.9997237,0.00004774759,0.00003253492,0.00004720765,0.00009390377,0.00005483328],"domain_scores_gemma":[0.9997676,0.00009058819,0.00004932386,0.0000273126,0.00001977208,0.00004536652],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002977042,0.00001456309,0.00007851978,0.000008906604,0.000003601945,0.00003032761,0.000006118134,0.00005832841,0.9994528,0.0000619521,0.000006694427,0.0002484542],"study_design_scores_gemma":[0.000008461047,0.00007680467,0.002846307,0.000001737937,0.000009513211,0.0001282649,0.00001571739,0.0008078055,0.9955382,0.00003290612,0.0005296993,0.000004728796],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9981753,0.0002063184,0.000935278,0.00003379468,0.00001030579,0.00001268022,0.0001135488,0.00003398938,0.0004788385],"genre_scores_gemma":[0.9985853,0.0001627473,0.0005549412,0.00002869301,0.000002814741,0.00001264058,0.0001075609,0.00001775107,0.0005276329],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001669248,"threshold_uncertainty_score":0.00558424,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01124161936818744,"score_gpt":0.2508742538494328,"score_spread":0.2396326344812454,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}