{"id":"W2076453815","doi":"10.1210/en.2014-1296","title":"β-Catenin Stabilization in Gonadotropes Impairs FSH Synthesis in Male Mice In Vivo","year":2014,"lang":"en","type":"article","venue":"Endocrinology","topic":"Reproductive Biology and Fertility","field":"Medicine","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; McGill University","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; Canadian Institutes of Health Research","keywords":"Follistatin; Internal medicine; Endocrinology; Exon; Gonadotropic cell; Gonadotropin; Biology; Gonadotropin-releasing hormone; Follicle-stimulating hormone; Wnt signaling pathway; Luteinizing hormone; Signal transduction; Hormone; Gene; Cell biology; Medicine; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002994247,0.0008081413,0.0004014975,0.001329714,0.0003265098,0.0006701145,0.0003975035,0.0007839862,0.004554297],"category_scores_gemma":[0.0001906782,0.0006230661,0.0005751591,0.0002924867,0.0006378168,0.0003798628,0.0002895101,0.001346791,0.001040081],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005376898,"about_ca_system_score_gemma":0.0003674334,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001182334,"about_ca_topic_score_gemma":0.001969737,"domain_scores_codex":[0.9995922,0.00004688323,0.00004780578,0.0001241019,0.0001059171,0.00008308377],"domain_scores_gemma":[0.9995008,0.00006034935,0.0002056979,0.00004689969,0.00002001216,0.0001663716],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002062958,0.00009770901,0.0002656934,0.00002371883,0.00001097479,0.0001290101,0.00002222185,0.0000657609,0.9981107,0.000165468,0.00005386718,0.0008485917],"study_design_scores_gemma":[0.00009673003,0.0006033626,0.006609276,0.00001608299,0.00003958832,0.0008090182,0.00006256382,0.0009062855,0.9884985,0.0001184874,0.002229245,0.00001092691],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9907714,0.001605951,0.002954334,0.0003760606,0.0001086851,0.00006457981,0.001387032,0.0004257848,0.002306229],"genre_scores_gemma":[0.983622,0.001112709,0.001638002,0.0001920435,0.00003620213,0.00009491731,0.001133905,0.0001786994,0.01199135],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004554297,"threshold_uncertainty_score":0.01523566,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0157157799128842,"score_gpt":0.2630844764076514,"score_spread":0.2473686964947672,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}