{"id":"W2076455738","doi":"10.1002/jps.20186","title":"A di(bisphosphonic acid) for protein coupling and targeting to bone","year":2004,"lang":"en","type":"article","venue":"Journal of Pharmaceutical Sciences","topic":"Bone health and treatments","field":"Medicine","cited_by":23,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research; Fondation pour la Recherche Médicale","keywords":"Bovine serum albumin; Chemistry; Conjugated system; Moiety; Conjugate; In vitro; Antibody; Bone mineral; Serum albumin; Biochemistry; Stereochemistry; Osteoporosis; Biology; Organic chemistry; Endocrinology; Immunology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008803171,0.00007837813,0.0002141821,0.00007424285,0.0001874383,0.00003001715,0.00005839214,0.00003082406,0.00001680676],"category_scores_gemma":[0.0002982004,0.00005028661,0.00005737475,0.0002172634,0.0001144441,0.0001191727,0.00002102425,0.0001492523,0.00000408489],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008017429,"about_ca_system_score_gemma":0.0003021297,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001543543,"about_ca_topic_score_gemma":0.000002865532,"domain_scores_codex":[0.9989197,0.000006864489,0.0003137098,0.0001293907,0.0003196397,0.0003106511],"domain_scores_gemma":[0.999157,0.00004239124,0.0001081413,0.00003092155,0.00009869095,0.000562867],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.005902553,0.002256328,0.06506389,0.001091091,0.0002760453,0.0007626378,0.001735227,0.001064169,0.7701121,0.005574763,0.0007767301,0.1453845],"study_design_scores_gemma":[0.02937223,0.01432401,0.02220583,0.002177262,0.0006085435,0.00186548,0.0008995557,0.006857219,0.8735151,0.007086304,0.04050551,0.0005829819],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.981079,0.003464513,0.001504179,0.01327392,0.0001381852,0.0004622079,0.000001509777,0.000007921469,0.0000685998],"genre_scores_gemma":[0.9793463,0.00008603261,0.01951276,0.0009217807,0.00008977963,0.000009990375,1.678069e-7,0.000005025125,0.00002815561],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1448015,"threshold_uncertainty_score":0.2050628,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0652678844625636,"score_gpt":0.416361526933512,"score_spread":0.3510936424709484,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}