{"id":"W2076487974","doi":"10.4161/epi.29068","title":"Functional DNA methylation in a transcript specific 3′UTR region of TrkB associates with suicide","year":2014,"lang":"en","type":"article","venue":"Epigenetics","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":74,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Douglas Mental Health University Institute; Douglas College","funders":"U.S. Public Health Service; National Institutes of Health","keywords":"Tropomyosin receptor kinase B; DNA methylation; Biology; Methylation; Epigenetics; Untranslated region; Gene; Molecular biology; Genetics; Gene expression; Messenger RNA; Neurotrophic factors; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000381426,0.0001620374,0.0002022127,0.00009973147,0.00004350001,0.00001375712,0.0001055859,0.0001807399,0.0000151664],"category_scores_gemma":[0.00007169486,0.0001537231,0.00007561169,0.0001868919,0.00007367835,0.00000414517,0.00002002779,0.00008879127,0.000003501071],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002207489,"about_ca_system_score_gemma":0.00004542919,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002411454,"about_ca_topic_score_gemma":0.0002182258,"domain_scores_codex":[0.9987388,0.0001480245,0.0003530963,0.0003188117,0.0002220523,0.000219217],"domain_scores_gemma":[0.9992929,0.0000467324,0.0001695086,0.0002924649,0.0001398432,0.00005860756],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001557869,0.0001119085,0.05238798,0.00002080387,0.00003399553,0.000001331089,0.0001247124,0.005103025,0.9325251,0.0003339304,0.0001270072,0.009074424],"study_design_scores_gemma":[0.0009905761,0.0005895777,0.2379486,0.00002669377,0.00001918887,0.00000175143,0.0000428839,0.0002512572,0.744324,0.001177502,0.0144032,0.0002247275],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9351875,0.002248665,0.06104087,0.0001216201,0.0001286425,0.0001748536,0.000008364691,0.000008175775,0.001081292],"genre_scores_gemma":[0.9965238,0.0008411183,0.001913133,0.00003681665,0.0001859414,0.00001271382,0.0001784409,0.0000296735,0.0002783808],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1882011,"threshold_uncertainty_score":0.6268644,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02095848577410384,"score_gpt":0.2329090938017164,"score_spread":0.2119506080276126,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}