{"id":"W2076487974","doi":"10.4161/epi.29068","title":"Functional DNA methylation in a transcript specific 3′UTR region of TrkB associates with suicide","year":2014,"lang":"en","type":"article","venue":"Epigenetics","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":74,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Douglas Mental Health University Institute; Douglas College","funders":"U.S. Public Health Service; National Institutes of Health","keywords":"Tropomyosin receptor kinase B; DNA methylation; Biology; Methylation; Epigenetics; Untranslated region; Gene; Molecular biology; Genetics; Gene expression; Messenger RNA; Neurotrophic factors; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009249793,0.0002483136,0.0002937465,0.0004199589,0.0001203472,0.000166607,0.0001611592,0.0002264076,0.002069341],"category_scores_gemma":[0.0003510379,0.0001392927,0.0002367797,0.0001693122,0.0002299934,0.00007112798,0.0001685566,0.0003212114,0.0002999324],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001239247,"about_ca_system_score_gemma":0.00007594944,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008116995,"about_ca_topic_score_gemma":0.0007802838,"domain_scores_codex":[0.9998709,0.00001669034,0.00001302615,0.00004441577,0.00003326807,0.0000217855],"domain_scores_gemma":[0.9995676,0.00004336574,0.000249221,0.00003645397,0.00004368727,0.00005960379],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0003432058,0.00001458405,0.01928301,0.00003296243,0.00003439752,0.0002076348,0.00008656381,0.00004383444,0.9776243,0.00002447757,0.00003259868,0.002272522],"study_design_scores_gemma":[0.00002065644,0.0005425073,0.7867974,0.00001382107,0.0001015087,0.005455004,0.0001517095,0.0005853372,0.2053926,0.0001336233,0.0007896245,0.00001617403],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9987084,0.0002690173,0.0006510296,0.00001463037,0.000002011974,0.000004286026,0.0001266412,0.00002500965,0.0001989605],"genre_scores_gemma":[0.9989171,0.0001212812,0.0003208188,0.000008075227,0.00000157751,0.000008108456,0.0001780986,0.000008573912,0.000436392],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002069341,"threshold_uncertainty_score":0.006922662,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02095848577410384,"score_gpt":0.2329090938017164,"score_spread":0.2119506080276126,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}