{"id":"W2076488716","doi":"10.3109/08982104.2015.1025411","title":"Production of limit size nanoliposomal systems with potential utility as ultra-small drug delivery agents","year":2015,"lang":"en","type":"article","venue":"Journal of Liposome Research","topic":"Lipid Membrane Structure and Behavior","field":"Biochemistry, Genetics and Molecular Biology","cited_by":38,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research","keywords":"Drug delivery; Liposome; Vesicle; Phosphatidylcholine; POPC; Microfluidics; Chemistry; Lipid bilayer; Nanotechnology; Bilayer; Drug; Materials science; Drug carrier; Chromatography; Chemical engineering; Membrane; Pharmacology; Biochemistry; Phospholipid","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001703839,0.0001546248,0.0003016716,0.0001526967,0.00008636575,0.00004811551,0.0003873468,0.0001505443,0.00001628842],"category_scores_gemma":[0.0004626322,0.0001103174,0.0001325187,0.0002399605,0.0002249313,0.0000237431,0.00008332171,0.000411573,0.000006441445],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005221361,"about_ca_system_score_gemma":0.0008743621,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001245816,"about_ca_topic_score_gemma":0.00002101812,"domain_scores_codex":[0.997393,0.0003921759,0.0004908085,0.0002714391,0.001055449,0.0003971336],"domain_scores_gemma":[0.9968429,0.00003331769,0.0002971513,0.0003721079,0.00214486,0.0003096884],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001918943,0.0002532345,0.006723701,0.0001276526,0.0001499839,0.00006627327,0.0001629488,0.000107409,0.9875452,0.000003858854,0.001976031,0.0009647946],"study_design_scores_gemma":[0.001329759,0.001977652,0.006972632,0.0001182266,0.00007948971,0.001048419,0.0007971763,0.000006540151,0.9829056,0.0000205488,0.004597573,0.0001463473],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9974074,0.0006965748,0.00001071866,0.0002158008,0.0009650182,0.0002871262,0.000008054312,0.000003975075,0.0004052944],"genre_scores_gemma":[0.9963527,0.0002316261,0.0001997351,0.00001207073,0.001670304,0.000005189198,0.000007870153,0.00002308791,0.00149743],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004639533,"threshold_uncertainty_score":0.4498612,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05268326712485773,"score_gpt":0.3184698993103054,"score_spread":0.2657866321854477,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}