{"id":"W2076506641","doi":"10.2337/dc14-0315","title":"Dapagliflozin’s Effects on Glycemia and Cardiovascular Risk Factors in High-Risk Patients With Type 2 Diabetes: A 24-Week, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study With a 28-Week Extension","year":2015,"lang":"en","type":"article","venue":"Diabetes Care","topic":"Diabetes Treatment and Management","field":"Medicine","cited_by":184,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; St. Michael's Hospital","funders":"Janssen Biotech; National Institutes of Health; Servier; Sanofi; Halozyme; National Institute of General Medical Sciences; Novo Nordisk; Intarcia Therapeutics; MannKind Corporation; GlaxoSmithKline; AstraZeneca; Eli Lilly and Company; Bristol-Myers Squibb","keywords":"Medicine; Dapagliflozin; Diabetes mellitus; Placebo; Type 2 diabetes; Internal medicine; Randomized controlled trial; Multicenter study; Endocrinology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00289827,0.001753293,0.003913266,0.0006708091,0.0005242671,0.00102243,0.001004159,0.002096733,0.003264576],"category_scores_gemma":[0.002042178,0.001263806,0.00228666,0.0006154651,0.001396928,0.001214571,0.0004983383,0.00293045,0.0005583844],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005563884,"about_ca_system_score_gemma":0.0008450719,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006463458,"about_ca_topic_score_gemma":0.001089085,"domain_scores_codex":[0.9987864,0.0006141562,0.0001140671,0.0002292303,0.0001262367,0.0001299737],"domain_scores_gemma":[0.9986212,0.0003270158,0.0003303998,0.0001577645,0.0001099154,0.0004537308],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9649178,0.01755674,0.001003718,0.0003119019,0.0006999376,0.00002605212,0.00003254965,0.0002009502,0.003991477,0.00001832565,0.0001686197,0.01107184],"study_design_scores_gemma":[0.9043713,0.0903554,0.003810133,0.00001116086,0.000365862,0.00001954629,0.000008307254,0.0002688889,0.0005988346,0.00001908986,0.0001594562,0.00001195543],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9945804,0.002242385,0.0004982272,0.0002104806,0.0002344017,0.001400935,0.0003505956,0.00006514411,0.0004173135],"genre_scores_gemma":[0.9918435,0.001573828,0.001698457,0.0004482129,0.0006461022,0.002296496,0.0004812947,0.00001576831,0.0009964168],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003913266,"threshold_uncertainty_score":0.01532775,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01215575304509195,"score_gpt":0.2222412732143134,"score_spread":0.2100855201692215,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}