{"id":"W2076506641","doi":"10.2337/dc14-0315","title":"Dapagliflozin’s Effects on Glycemia and Cardiovascular Risk Factors in High-Risk Patients With Type 2 Diabetes: A 24-Week, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study With a 28-Week Extension","year":2015,"lang":"en","type":"article","venue":"Diabetes Care","topic":"Diabetes Treatment and Management","field":"Medicine","cited_by":184,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; St. Michael's Hospital","funders":"Janssen Biotech; National Institutes of Health; Servier; Sanofi; Halozyme; National Institute of General Medical Sciences; Novo Nordisk; Intarcia Therapeutics; MannKind Corporation; GlaxoSmithKline; AstraZeneca; Eli Lilly and Company; Bristol-Myers Squibb","keywords":"Medicine; Dapagliflozin; Diabetes mellitus; Placebo; Type 2 diabetes; Internal medicine; Randomized controlled trial; Multicenter study; Endocrinology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0008083588,0.0008069248,0.002669715,0.0005098482,0.0001368363,0.0001086235,0.0001604154,0.0001759055,0.000007362879],"category_scores_gemma":[0.0004516513,0.0004835522,0.0003313747,0.000477179,0.0001406439,0.0002151751,0.0001378497,0.0004731777,0.00003920925],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003010893,"about_ca_system_score_gemma":0.00008056702,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003731583,"about_ca_topic_score_gemma":0.0001708186,"domain_scores_codex":[0.9957229,0.0007046763,0.0005315383,0.00106635,0.001172311,0.0008022467],"domain_scores_gemma":[0.9970131,0.0006914274,0.0003185098,0.0009951517,0.0005240969,0.0004577488],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.342049,0.00161652,0.6465366,0.0001664176,0.004918085,0.00004249808,0.001871942,0.0003082383,0.000001596559,0.00000108729,0.00008863954,0.002399296],"study_design_scores_gemma":[0.822604,0.01457486,0.1497188,0.0006286084,0.008762116,7.993169e-8,0.002557361,0.0002836992,0.000226683,0.000004560564,0.000133688,0.0005055734],"study_design_candidate":"randomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9818928,0.002056347,0.000003144522,0.0000179308,0.0004167453,0.0152629,0.00003819981,0.0001461119,0.0001658741],"genre_scores_gemma":[0.99747,0.0001035621,0.0001663181,0.000119422,0.00007420273,0.001475533,0.000409126,0.0001222966,0.00005957713],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4968179,"threshold_uncertainty_score":0.9997616,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01215575304509195,"score_gpt":0.2222412732143134,"score_spread":0.2100855201692215,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}