{"id":"W2076607155","doi":"10.1002/jcp.22787","title":"Integrating post‐transcriptional regulation into the embryonic stem cell gene regulatory network","year":2011,"lang":"en","type":"review","venue":"Journal of Cellular Physiology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ottawa Hospital; University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Biology; Embryonic stem cell; Epigenetics; Gene regulatory network; Regulation of gene expression; Gene; Stem cell; Computational biology; Gene expression; Transcriptional regulation; Cell fate determination; Transcription factor; Cell biology; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005832424,0.0003945395,0.0008919092,0.00009088113,0.0001213004,0.00001863853,0.0005705234,0.0004931279,0.00003608733],"category_scores_gemma":[0.0000145498,0.0002629436,0.000875627,0.0001290122,0.0001069081,0.000006225013,0.000108894,0.0005707093,0.00001070013],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004320504,"about_ca_system_score_gemma":0.0003018684,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003173016,"about_ca_topic_score_gemma":0.000004178532,"domain_scores_codex":[0.9979976,0.0003520251,0.0008612641,0.0003088019,0.0001621934,0.0003181457],"domain_scores_gemma":[0.9982319,0.00004597289,0.0008881774,0.0005028956,0.0002384746,0.00009251651],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00006105089,0.00005348922,9.863866e-7,0.001411812,0.0004167187,0.000007037108,0.0001622856,0.0009739303,0.7588823,0.0003297245,0.001191147,0.2365095],"study_design_scores_gemma":[0.0002482962,0.0004620076,0.00007122077,0.0009510209,0.0005831205,0.0001482431,0.00005857841,0.00003329199,0.01821004,0.0002280171,0.9786189,0.000387277],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00444227,0.9837602,0.01039334,0.0000133672,0.001072882,0.0002151347,0.000004275201,0.000005519558,0.00009295865],"genre_scores_gemma":[0.01271253,0.9821947,0.00129854,0.00005227467,0.003030038,0.00001209268,0.0001611745,0.00007588187,0.0004627987],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9774277,"threshold_uncertainty_score":0.9999823,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01301800519981695,"score_gpt":0.2674419047996265,"score_spread":0.2544238995998095,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}