{"id":"W2076614371","doi":"10.4236/ijcm.2011.22022","title":"Glucose Metabolism in Breast Cancer and its Implication in Cancer Therapy","year":2011,"lang":"en","type":"article","venue":"International Journal of Clinical Medicine","topic":"Cancer, Hypoxia, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"Fundo para o Desenvolvimento das Ciências e da Tecnologia","keywords":"GLUT1; Pentose phosphate pathway; Glycolysis; Glucose transporter; Glucose uptake; Glucose Transporter Type 1; Fatty acid synthesis; Carbohydrate metabolism; Oxidative phosphorylation; Biology; Cancer cell; Metabolism; Endocrinology; Anaerobic glycolysis; Internal medicine; Cancer research; Cancer; Biochemistry; Fatty acid; Insulin; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007465574,0.00009563071,0.0003097428,0.0001257443,0.000007506353,0.000004263998,0.0002412931,0.0001062707,0.0001591921],"category_scores_gemma":[0.0001893604,0.00006974334,0.00006968869,0.00007200488,0.00007877593,0.00001446038,0.00003780152,0.0002114393,6.580826e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001606896,"about_ca_system_score_gemma":0.0001570649,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004754808,"about_ca_topic_score_gemma":0.0002822952,"domain_scores_codex":[0.9986398,0.00006662157,0.000790164,0.0001657347,0.0002255116,0.0001122188],"domain_scores_gemma":[0.9990386,0.00003849434,0.000371062,0.00008254175,0.0003661635,0.0001030767],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.003992267,0.0005387744,0.1983814,0.0000102848,0.0003540102,0.00002102446,0.0005793619,0.00001659797,0.1780122,0.0005256842,0.002697225,0.6148711],"study_design_scores_gemma":[0.005071261,0.0001296918,0.9220728,0.000122783,0.00002116154,0.00007406287,0.00004002595,0.00002091765,0.006060577,0.0003129731,0.06598832,0.00008548504],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9539591,0.03728796,0.00002575108,0.005018353,0.003380114,0.00007810586,0.00001730043,0.00000131304,0.0002319757],"genre_scores_gemma":[0.8405517,0.1530153,0.0000566269,0.001293782,0.00500388,0.00001105015,0.000003424711,0.000008466141,0.00005574624],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7236913,"threshold_uncertainty_score":0.2844051,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06066911209701981,"score_gpt":0.4171237162526555,"score_spread":0.3564546041556357,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}