{"id":"W2076643977","doi":"10.1203/pdr.0b013e31815ed059","title":"Developmental Absence of the O2 Sensitivity of L-Type Calcium Channels in Preterm Ductus Arteriosus Smooth Muscle Cells Impairs O2 Constriction Contributing to Patent Ductus Arteriosus","year":2008,"lang":"en","type":"article","venue":"Pediatric Research","topic":"Neuroscience of respiration and sleep","field":"Neuroscience","cited_by":60,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"National Heart, Lung, and Blood Institute; Canadian Institutes of Health Research; National Institutes of Health; Fondation pour la Recherche Médicale; Heart and Stroke Foundation of Canada","keywords":"Ductus arteriosus; Constriction; Internal medicine; Depolarization; Bay K8644; Vasoconstriction; Endocrinology; L-type calcium channel; Calcium; Cardiology; Activator (genetics); Medicine; Voltage-dependent calcium channel; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004192549,0.0004377711,0.0005911131,0.0005539326,0.0006395485,0.0009571676,0.0009943419,0.0009430319,0.003291316],"category_scores_gemma":[0.001045825,0.0006186456,0.0005122864,0.0002474515,0.001441001,0.0008163666,0.0009333182,0.002323806,0.0008020262],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006732807,"about_ca_system_score_gemma":0.0008840853,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00241798,"about_ca_topic_score_gemma":0.002777004,"domain_scores_codex":[0.9992704,0.000108178,0.000147602,0.0001169576,0.0002038136,0.0001531024],"domain_scores_gemma":[0.9985196,0.0005010646,0.0003484261,0.0002080978,0.00008814324,0.0003347871],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001160777,0.0000330386,0.0001626651,0.00002305859,0.000004494404,0.0001840676,0.00007504889,0.00006246576,0.9983449,0.0003833755,0.0000382367,0.0005725053],"study_design_scores_gemma":[0.00005134413,0.0001179287,0.005835971,0.00001848397,0.00003174002,0.0006586806,0.0002975252,0.001604233,0.9889067,0.0003039407,0.002157938,0.00001544416],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9919624,0.0005170866,0.004955998,0.0003828809,0.00009722157,0.00003019929,0.000444581,0.0001142962,0.001495348],"genre_scores_gemma":[0.9939368,0.0006299207,0.002258824,0.00009461192,0.00002450287,0.00005952105,0.0002451137,0.0001188718,0.002631777],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003291316,"threshold_uncertainty_score":0.01101053,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1245333079671226,"score_gpt":0.3242545600304191,"score_spread":0.1997212520632964,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}