{"id":"W2076643977","doi":"10.1203/pdr.0b013e31815ed059","title":"Developmental Absence of the O2 Sensitivity of L-Type Calcium Channels in Preterm Ductus Arteriosus Smooth Muscle Cells Impairs O2 Constriction Contributing to Patent Ductus Arteriosus","year":2008,"lang":"en","type":"article","venue":"Pediatric Research","topic":"Neuroscience of respiration and sleep","field":"Neuroscience","cited_by":60,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"National Heart, Lung, and Blood Institute; Canadian Institutes of Health Research; National Institutes of Health; Fondation pour la Recherche Médicale; Heart and Stroke Foundation of Canada","keywords":"Ductus arteriosus; Constriction; Internal medicine; Depolarization; Bay K8644; Vasoconstriction; Endocrinology; L-type calcium channel; Calcium; Cardiology; Activator (genetics); Medicine; Voltage-dependent calcium channel; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002047427,0.0001888241,0.0003081683,0.0005592844,0.0004920607,0.00005442967,0.0004446832,0.00008814577,0.00002838707],"category_scores_gemma":[0.003133931,0.000153821,0.00008720627,0.003018029,0.0005079411,0.0002214801,0.000427162,0.0004316622,0.00002842745],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001827642,"about_ca_system_score_gemma":0.0005714358,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002447905,"about_ca_topic_score_gemma":0.00002181189,"domain_scores_codex":[0.9954478,0.0009614022,0.0006188598,0.0006377607,0.001399224,0.0009349476],"domain_scores_gemma":[0.9980446,0.0008364035,0.0002194742,0.0003275432,0.0003568792,0.0002150982],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009621189,0.0001438974,0.03261392,0.00003742628,0.000001001525,0.0001802296,0.001055883,0.0004154126,0.9642306,0.00001886924,0.0001302844,0.001076286],"study_design_scores_gemma":[0.0008311913,0.0004787843,0.3091539,0.00002728099,0.000004254919,0.0001204645,0.0003332306,0.003262037,0.6853474,0.00002259458,0.0001703841,0.0002484221],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9974948,0.00002172131,0.0001504744,0.0002228309,0.0008616785,0.0009348104,0.00003453576,0.00002553768,0.0002535737],"genre_scores_gemma":[0.9994415,0.000151445,0.00006329615,0.0001013627,0.0001230058,0.0000205809,7.300093e-7,0.0000151011,0.00008297409],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2788831,"threshold_uncertainty_score":0.627264,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1245333079671226,"score_gpt":0.3242545600304191,"score_spread":0.1997212520632964,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}