{"id":"W2076743305","doi":"10.1074/jbc.m403367200","title":"The Adaptor Protein Bam32 Regulates Rac1 Activation and Actin Remodeling through a Phosphorylation-dependent Mechanism","year":2004,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":38,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"National Institute of Allergy and Infectious Diseases","keywords":"Signal transducing adaptor protein; Cell biology; RAC1; Phosphorylation; Proto-oncogene tyrosine-protein kinase Src; Biology; Actin; Tyrosine phosphorylation; breakpoint cluster region; Rac GTP-Binding Proteins; Pleckstrin homology domain; Actin remodeling; Cytoskeleton; Actin cytoskeleton; Pseudopodia; Myristoylation; Signal transduction; Receptor; Cell; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001556895,0.0004319174,0.0001660087,0.0002284823,0.0003346491,0.0003092021,0.0002229914,0.000332661,0.002074069],"category_scores_gemma":[0.0001441134,0.0001996454,0.0002476412,0.0001253901,0.0001968125,0.0002973622,0.0003271071,0.0005717515,0.0008728565],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003050132,"about_ca_system_score_gemma":0.0001882393,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000403198,"about_ca_topic_score_gemma":0.0004229564,"domain_scores_codex":[0.999836,0.00003235249,0.000007291285,0.00003161356,0.00004449957,0.00004827854],"domain_scores_gemma":[0.9998919,0.000009540164,0.00003040634,0.00001105312,0.00002075723,0.00003633021],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001500622,0.00003245965,0.000208837,0.00003452275,0.000004088167,0.00006453656,0.00001478447,0.00007773518,0.9973253,0.0002467928,0.0001452232,0.001695752],"study_design_scores_gemma":[0.0000903212,0.0002939797,0.02108336,0.00002004119,0.00002118987,0.0007779476,0.00006162532,0.006291307,0.9600021,0.0002971091,0.01104311,0.0000179357],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9876528,0.003501606,0.004357784,0.0002606111,0.00006141909,0.00005556876,0.0003209677,0.0002329491,0.003556287],"genre_scores_gemma":[0.9932443,0.001063994,0.001976289,0.00004139182,0.00001521804,0.00006526054,0.0003481731,0.00001914763,0.00322599],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002074069,"threshold_uncertainty_score":0.006938457,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01922277185346809,"score_gpt":0.226164914098005,"score_spread":0.2069421422445369,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}