{"id":"W2076749894","doi":"10.1089/scd.2012.0315","title":"Cord-Blood-Derived Mesenchymal Stromal Cells Downmodulate CD4 <sup>+</sup> T-Cell Activation by Inducing IL-10-Producing Th1 Cells","year":2012,"lang":"en","type":"article","venue":"Stem Cells and Development","topic":"Mesenchymal stem cell research","field":"Medicine","cited_by":41,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre Hospitalier Universitaire Sainte-Justine; Université de Montréal","funders":"National Institute of Allergy and Infectious Diseases; Fonds de Recherche du Québec - Santé; CHU Sainte-Justine Foundation; Fondation Charles-Bruneau","keywords":"Biology; Mesenchymal stem cell; Flow cytometry; IL-2 receptor; Cell biology; T cell; Stromal cell; Interleukin 21; Population; Cytokine; Molecular biology; Interleukin 12; Immune system; Immunology; Cytotoxic T cell; Cancer research; In vitro; Medicine; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.001564651,0.0007065878,0.0008497541,0.0003152987,0.0005222867,0.0001614581,0.000278765,0.0003693687,0.001059484],"category_scores_gemma":[0.00002451819,0.0006170111,0.0001228685,0.0004489475,0.0001330266,0.0004530284,0.00041938,0.0006971376,0.0005861419],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003467438,"about_ca_system_score_gemma":0.0005055562,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001560458,"about_ca_topic_score_gemma":0.000002570735,"domain_scores_codex":[0.9944829,0.0002369723,0.001011378,0.001164519,0.001411501,0.001692766],"domain_scores_gemma":[0.9973461,0.0002473687,0.0003286108,0.000707048,0.0002871095,0.001083742],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002952595,0.0005788911,0.002704906,0.0007501302,0.0001726552,0.00003397712,0.004541989,0.0001076149,0.9716251,0.000005374904,0.006767543,0.01241656],"study_design_scores_gemma":[0.002341896,0.0003815542,0.002309345,0.0002649095,0.00008506238,0.00002736001,0.001663109,0.0003804478,0.9580103,0.00000232158,0.03386096,0.0006727293],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9908884,0.0007498871,0.0004514118,0.0001364072,0.0004029406,0.001534489,0.00003160863,0.0001306322,0.005674292],"genre_scores_gemma":[0.9710762,0.0002405853,0.007700511,0.0001949647,0.000328427,0.00008104863,0.000100756,0.0001166729,0.02016087],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02709342,"threshold_uncertainty_score":0.9998537,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03084722182875949,"score_gpt":0.2566657033905888,"score_spread":0.2258184815618293,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}