{"id":"W2076749894","doi":"10.1089/scd.2012.0315","title":"Cord-Blood-Derived Mesenchymal Stromal Cells Downmodulate CD4 <sup>+</sup> T-Cell Activation by Inducing IL-10-Producing Th1 Cells","year":2012,"lang":"en","type":"article","venue":"Stem Cells and Development","topic":"Mesenchymal stem cell research","field":"Medicine","cited_by":41,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre Hospitalier Universitaire Sainte-Justine; Université de Montréal","funders":"National Institute of Allergy and Infectious Diseases; Fonds de Recherche du Québec - Santé; CHU Sainte-Justine Foundation; Fondation Charles-Bruneau","keywords":"Biology; Mesenchymal stem cell; Flow cytometry; IL-2 receptor; Cell biology; T cell; Stromal cell; Interleukin 21; Population; Cytokine; Molecular biology; Interleukin 12; Immune system; Immunology; Cytotoxic T cell; Cancer research; In vitro; Medicine; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001476659,0.0005775355,0.0003101548,0.000282033,0.00007843512,0.0003430914,0.000136356,0.0002226103,0.001863478],"category_scores_gemma":[0.0001042359,0.0001029725,0.000304624,0.0001806462,0.0002319145,0.0001277225,0.0001716424,0.0006295288,0.0006360564],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001570505,"about_ca_system_score_gemma":0.0002484403,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003031676,"about_ca_topic_score_gemma":0.000571615,"domain_scores_codex":[0.999803,0.0000366453,0.0000300494,0.00002852926,0.0000564623,0.0000452544],"domain_scores_gemma":[0.9998595,0.00002218372,0.00005109329,0.00001563672,0.00001820749,0.00003335505],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001399452,0.00004214032,0.0002341315,0.00006993747,0.000006297464,0.00006685819,0.0000110427,0.00005238429,0.9965112,0.00003665022,0.00002833042,0.002801132],"study_design_scores_gemma":[0.0000130936,0.0003706344,0.002148412,0.000008572819,0.00002940305,0.0001877227,0.00002052936,0.0003618538,0.9947477,0.00003491742,0.002075164,0.000002086882],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9874783,0.00321703,0.006137978,0.0001545184,0.0001235583,0.00009007053,0.000457376,0.0001738322,0.002167345],"genre_scores_gemma":[0.9899951,0.001878801,0.004550486,0.0001319404,0.00007422346,0.00007952694,0.0006373386,0.00004023984,0.002612341],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001863478,"threshold_uncertainty_score":0.006233931,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03084722182875949,"score_gpt":0.2566657033905888,"score_spread":0.2258184815618293,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}