{"id":"W2076762694","doi":"10.1159/000329510","title":"N-Acetylcysteine Modulates the Cytotoxic Effects of Paclitaxel","year":2011,"lang":"en","type":"article","venue":"Chemotherapy","topic":"Cell death mechanisms and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"NOSM University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Paclitaxel; Apoptosis; Acetylcysteine; Cytotoxicity; Reactive oxygen species; Viability assay; A549 cell; Pharmacology; Chemistry; Programmed cell death; Intracellular; Biology; Cell biology; In vitro; Biochemistry; Chemotherapy; Antioxidant","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009446414,0.0002037953,0.0001749489,0.0001642609,0.0001090602,0.0002059243,0.0001645549,0.0001897008,0.0008269327],"category_scores_gemma":[0.0001802884,0.00006963962,0.000145028,0.0001491264,0.0001755091,0.0001257041,0.00006876871,0.000237321,0.0001844846],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003176123,"about_ca_system_score_gemma":0.0002137159,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007312382,"about_ca_topic_score_gemma":0.001388644,"domain_scores_codex":[0.9998934,0.0000251791,0.00001435587,0.00001316816,0.00003014066,0.00002373066],"domain_scores_gemma":[0.9999009,0.00001616603,0.00002715943,0.00001010543,0.00002653084,0.00001900973],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003662886,0.00005718226,0.0002954151,0.00004251484,0.00000847099,0.00005064817,0.000008883085,0.00006201378,0.997582,0.00003688072,0.00004778536,0.001441879],"study_design_scores_gemma":[0.00001923585,0.0006067047,0.003710333,0.000005247402,0.00002321296,0.0001286807,0.00001352524,0.0002846075,0.9940701,0.00001483466,0.001121064,0.000002356267],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9949096,0.002747546,0.0004100502,0.00007919826,0.00004060953,0.00003059778,0.0001264917,0.00003052654,0.0016254],"genre_scores_gemma":[0.99697,0.001422576,0.0003725296,0.00003986999,0.00001448579,0.00001790698,0.0001646513,0.000005496732,0.0009924558],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008269327,"threshold_uncertainty_score":0.002766311,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008151801064260467,"score_gpt":0.2062404286772485,"score_spread":0.198088627612988,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}