{"id":"W2076762694","doi":"10.1159/000329510","title":"N-Acetylcysteine Modulates the Cytotoxic Effects of Paclitaxel","year":2011,"lang":"en","type":"article","venue":"Chemotherapy","topic":"Cell death mechanisms and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"NOSM University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Paclitaxel; Apoptosis; Acetylcysteine; Cytotoxicity; Reactive oxygen species; Viability assay; A549 cell; Pharmacology; Chemistry; Programmed cell death; Intracellular; Biology; Cell biology; In vitro; Biochemistry; Chemotherapy; Antioxidant","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007500267,0.00008928069,0.00008953821,0.00001348707,0.00003468158,0.000003411486,0.0001165425,0.00008452895,0.00003405914],"category_scores_gemma":[0.000009473506,0.00005701662,0.00007641393,0.00004626788,0.00005627801,0.000001471279,0.00002075676,0.00002808614,0.000003143092],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000003088962,"about_ca_system_score_gemma":0.00001033422,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001280566,"about_ca_topic_score_gemma":0.000002171552,"domain_scores_codex":[0.9995677,0.00002146251,0.0001062224,0.0001377299,0.00006120517,0.0001056682],"domain_scores_gemma":[0.9995829,0.000007180588,0.00006179297,0.0002936554,0.00003063735,0.00002383357],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004401461,0.00004527011,0.0001405626,0.000025268,0.00003683036,4.000728e-7,0.0001954482,0.000003794389,0.993443,0.0002714579,0.0002213124,0.005572618],"study_design_scores_gemma":[0.000563121,0.0002597954,0.003961061,0.0000102918,0.0000077382,0.000003721411,0.00001928094,0.00006060695,0.990352,0.0006290469,0.004057913,0.00007546345],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9939864,0.001170437,0.003629133,0.00005745125,0.0001193814,0.0002189975,0.000001257321,0.000008827062,0.0008081428],"genre_scores_gemma":[0.9972808,0.0005350485,0.0007931586,0.0001813751,0.0001020069,0.00001306783,0.000009907994,0.00001760455,0.00106698],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005497155,"threshold_uncertainty_score":0.2325071,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008151801064260467,"score_gpt":0.2062404286772485,"score_spread":0.198088627612988,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}