{"id":"W2076822812","doi":"10.1152/ajpendo.00006.2014","title":"Pre-B cell colony enhancing factor induces Nampt-dependent translocation of the insulin receptor out of lipid microdomains in A549 lung epithelial cells","year":2014,"lang":"en","type":"article","venue":"American Journal of Physiology-Endocrinology and Metabolism","topic":"Caveolin-1 and cellular processes","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; St. Michael's Hospital","funders":"Canadian Institutes of Health Research; Physicians' Services Incorporated Foundation","keywords":"Lipid raft; Insulin receptor; Phosphorylation; Cell biology; A549 cell; Chemistry; Protein kinase B; Tyrosine phosphorylation; Signal transduction; Insulin; Biology; Cell; Biochemistry; Endocrinology; Insulin resistance","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001590723,0.0003326915,0.0003731818,0.0002081411,0.0001694708,0.000302674,0.0002088638,0.0002684964,0.001064481],"category_scores_gemma":[0.0001171185,0.0001786331,0.0004366306,0.0001769333,0.00015121,0.0001855586,0.0002639886,0.0007993745,0.0006021874],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003203199,"about_ca_system_score_gemma":0.0001656934,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00100947,"about_ca_topic_score_gemma":0.001122679,"domain_scores_codex":[0.9997975,0.0000351073,0.00002383719,0.0000373758,0.00005184051,0.00005435617],"domain_scores_gemma":[0.9998794,0.0000228741,0.000022371,0.00002009292,0.00001860761,0.00003664778],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007351507,0.0000225802,0.00005911808,0.00001996597,0.000002907092,0.00003570838,0.00001051203,0.00001198481,0.9994915,0.00002250407,0.00002164844,0.0002281315],"study_design_scores_gemma":[0.00003060015,0.0002547323,0.00656812,0.000007322216,0.000009659042,0.0002334808,0.00005371344,0.0008817366,0.9904509,0.00002632916,0.001478752,0.000004656637],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9942676,0.00131821,0.001880847,0.0001431843,0.00004102014,0.00005334165,0.0007579939,0.00007674806,0.001461034],"genre_scores_gemma":[0.9912437,0.0008250604,0.003056015,0.0001307553,0.00001269031,0.00009784794,0.001619311,0.00003453261,0.002980138],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001064481,"threshold_uncertainty_score":0.00356102,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004354708177338043,"score_gpt":0.2203522200006927,"score_spread":0.2159975118233547,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}