{"id":"W2076908570","doi":"10.1021/bi048251y","title":"Photolabeling Study of the Ligand Binding Domain of Natriuretic Peptide Receptor A: Development of a Model","year":2005,"lang":"en","type":"article","venue":"Biochemistry","topic":"Chemical Synthesis and Analysis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Montreal Clinical Research Institute; Institut National de la Recherche Scientifique; Université du Québec à Montréal","funders":"","keywords":"NPR2; Peptide; Natriuretic peptide; Receptor; NPR1; Chemistry; Cyclic guanosine monophosphate; Atrial natriuretic peptide; Peptide sequence; Amino acid; Binding site; Homology modeling; Biochemistry; Ligand (biochemistry); Protein structure; Biophysics; Biology; Internal medicine; Endocrinology; Medicine; Nitric oxide","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001061538,0.0002322477,0.0001907824,0.00009606439,0.0002046827,0.0001943126,0.0005252978,0.0004409888,0.0006645987],"category_scores_gemma":[0.00008370396,0.0001419186,0.0002430247,0.0001025919,0.0002163061,0.0002903612,0.0001594798,0.0006268621,0.0002711518],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005661961,"about_ca_system_score_gemma":0.0002513667,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001349588,"about_ca_topic_score_gemma":0.000837297,"domain_scores_codex":[0.9999479,0.00000769744,0.000001703044,0.00001931453,0.00001349544,0.000009954952],"domain_scores_gemma":[0.9999679,0.000008690592,0.000007822319,0.000003037276,0.000004368958,0.000008061943],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004281201,0.00003079701,0.00008644711,0.00004263783,0.000004056211,0.00007099358,0.00001550744,0.002391509,0.9948456,0.001392205,0.00004535471,0.001032081],"study_design_scores_gemma":[0.00004699065,0.0003421524,0.001044945,0.00001102345,0.00001692925,0.000380935,0.00004627956,0.06574606,0.9254647,0.0008007532,0.006081588,0.00001759542],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9514993,0.002667989,0.04074321,0.0004104095,0.00004440989,0.00005902276,0.0001682013,0.00008883066,0.004318626],"genre_scores_gemma":[0.9584095,0.002185692,0.03654207,0.00006586492,0.00001098856,0.00005787502,0.0002546443,0.00001883793,0.002454538],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001349588,"threshold_uncertainty_score":0.004108071,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0103496600808905,"score_gpt":0.2359294586236765,"score_spread":0.225579798542786,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}