{"id":"W2076942264","doi":"10.1002/pro.276","title":"An interdomain disulfide bridge links the NtA and first FS domain in agrin","year":2009,"lang":"en","type":"article","venue":"Protein Science","topic":"Ubiquitin and proteasome pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"Canadian Institutes of Health Research","keywords":"Agrin; Chemistry; Cysteine; Amino acid; Laminin; Biochemistry; Biophysics; Postsynaptic potential; Biology; Extracellular matrix","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001160656,0.0001184501,0.00008736676,0.00004934745,0.0002282011,0.0001119575,0.0005687243,0.00009225832,0.000007058593],"category_scores_gemma":[0.0001302206,0.00008425764,0.00002439836,0.0002530015,0.0004410665,0.00001720039,0.0001463588,0.0001812262,0.000006446573],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000168227,"about_ca_system_score_gemma":0.00007444855,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004652862,"about_ca_topic_score_gemma":0.0001906176,"domain_scores_codex":[0.9988299,0.00006998085,0.0001552631,0.0004416256,0.0001823464,0.0003208917],"domain_scores_gemma":[0.9993807,0.000008817407,0.0000492086,0.0004212974,0.00003125255,0.0001086995],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003386723,0.00004620945,0.001815753,0.000005445068,0.000001014286,0.000004399488,0.0003525528,0.000004108487,0.9818088,0.001178153,0.00003325567,0.01471643],"study_design_scores_gemma":[0.0004926469,0.0006950139,0.09023977,0.0000601991,0.00000187525,0.00003554174,0.0001286738,0.0001824122,0.8934276,0.00666025,0.007804647,0.0002713457],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9949726,0.0003019955,0.001080223,0.001629354,0.00003062872,0.0005032058,0.000005475359,0.0000110674,0.00146542],"genre_scores_gemma":[0.9974805,0.00002735313,0.001703762,0.0005549474,0.00009111276,0.00004904943,0.000004273427,0.000005599441,0.00008340415],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.08842402,"threshold_uncertainty_score":0.3435927,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01102188652398423,"score_gpt":0.2654184453539633,"score_spread":0.254396558829979,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}