{"id":"W2076951145","doi":"10.1016/j.toxrep.2014.05.002","title":"The combined effects of physicochemical properties of size-fractionated ambient particulate matter on in vitro toxicity in human A549 lung epithelial cells","year":2014,"lang":"en","type":"article","venue":"Toxicology Reports","topic":"Air Quality and Health Impacts","field":"Environmental Science","cited_by":98,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Michael's Hospital; Lakehead University; University of Toronto; University Health Network; NOSM University; Public Health Ontario","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Canada Foundation for Innovation; Ontario Research Foundation","keywords":"Proinflammatory cytokine; Chemistry; Antioxidant; Particulates; Toxicity; Environmental chemistry; Aerodynamic diameter; Oxidative stress; A549 cell; In vitro; Biochemistry; Inflammation; Immunology; Biology; Organic chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002197532,0.0003013182,0.0003176938,0.0002373742,0.0002201225,0.0003172192,0.0001079394,0.0002839083,0.0005405624],"category_scores_gemma":[0.0001890003,0.0001525976,0.0003827795,0.0002493171,0.0001607174,0.0001527181,0.0001904396,0.0002641011,0.0001433252],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003348623,"about_ca_system_score_gemma":0.0002378159,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004903004,"about_ca_topic_score_gemma":0.008830366,"domain_scores_codex":[0.9997428,0.00006929355,0.00003040482,0.00004265999,0.00007519298,0.0000395974],"domain_scores_gemma":[0.999815,0.00004800546,0.00002950038,0.00001944942,0.00006355342,0.00002448269],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000421822,0.00007214452,0.003090579,0.00009580775,0.00002884387,0.00007124833,0.00006783098,0.0001725059,0.9941637,0.00001513685,0.00003085814,0.001769572],"study_design_scores_gemma":[0.0000353689,0.004424527,0.1469604,0.00001564053,0.0001319006,0.000365737,0.0003663508,0.0008443404,0.8454335,0.00005891942,0.00134232,0.00002097633],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9968406,0.001745028,0.000464289,0.00003413482,0.00001268419,0.00002686564,0.0002559137,0.000007990607,0.0006124426],"genre_scores_gemma":[0.9972047,0.001084982,0.0005715674,0.00005796408,0.00001237077,0.00002925188,0.0003632497,0.000002938476,0.0006729311],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004903004,"threshold_uncertainty_score":0.009748936,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01178884581290831,"score_gpt":0.2632467494332165,"score_spread":0.2514579036203082,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}